10+ Techmihirnaik group Interview Questions and Answers

Tablet is a solid dosage form of medication. Tablet disintegration time is the time taken for a tablet to break down into smaller particles.

• Tablets are made by compressing a mixture of active ingredients and excipients.

• Disintegration time is important for drug absorption and efficacy.

• Factors affecting disintegration time include tablet composition, size, and shape.

• Disintegration time can be measured using various methods such as USP apparatus or disintegration testers.

• Example...read more

HPLC is a high-performance liquid chromatography used for separating, identifying, and quantifying components in a mixture.

• HPLC consists of a pump, injector, column, detector, and data system.

• The pump is used to deliver the mobile phase at a constant flow rate.

• The injector is used to introduce the sample into the mobile phase.

• The column is where the separation of components occurs.

• The detector is used to detect the separated components and generate a signal.

• The data system is...read more

Coating of tablets is a process where a thin layer is applied to the tablet to improve appearance, taste, and stability.

• Coating helps in masking the taste of the drug, making it easier for patients to swallow.

• It also protects the drug from moisture, light, and air, increasing its stability and shelf life.

• Different types of coatings can be used such as sugar coating, film coating, and enteric coating.

• Coating can also be used for controlled release of the drug, where the coatin...read more

Effervescent tablets are tablets that are designed to dissolve in water, releasing carbon dioxide and creating a fizzy effervescent solution.

• Effervescent tablets are commonly used for pain relief, vitamin supplementation, and indigestion relief.

• They are convenient for people who have difficulty swallowing pills.

• Examples include Alka-Seltzer, Berocca, and Emergen-C.

• They typically contain citric acid and sodium bicarbonate as the active ingredients.

The known, unknown, imp formula is a concept used in training to emphasize the importance of understanding what is known, what is unknown, and what is important.

• Known: Information that is already familiar or established

• Unknown: Information that is not yet understood or discovered

• Imp: Information that is crucial or significant

• Example: Before starting a project, identify what is known, what is unknown, and what is important to achieve success

FBD stands for Free Body Diagram, a diagram used to represent the forces acting on a body in a given situation.

• FBD is a visual representation of all the forces acting on a body in a particular situation

• It helps in analyzing and solving problems related to mechanics and dynamics

• The forces are typically represented by arrows pointing in the direction of the force and labeled with their magnitude and direction

• Common forces shown in FBDs include weight, normal force, tension, fri...read more

ALCOVA stands for Analyze, Locate, Control, Organize, Verify, and Act

• ALCOVA is a problem-solving method used in engineering and management

• Analyze - thoroughly examine the problem

• Locate - identify the root cause or source of the problem

• Control - implement measures to prevent recurrence

• Organize - plan and organize the solution

• Verify - confirm the effectiveness of the solution

• Act - take necessary actions based on the analysis

21CFR refers to Title 21 of the Code of Federal Regulations, which contains regulations related to food and drugs in the United States.

• 21CFR is divided into different parts, with each part focusing on specific aspects such as food labeling, medical devices, pharmaceuticals, etc.

• It is important for companies in the food and drug industry to comply with the regulations outlined in 21CFR to ensure product safety and quality.

• For example, 21CFR Part 11 pertains to electronic recor...read more

Validation is the process of ensuring that data or information is accurate, reliable, and meets certain criteria or standards.

• Validation involves checking data for accuracy, consistency, and completeness.

• It helps to ensure that data is reliable and meets certain criteria or standards.

• Validation can be done through various methods such as data entry validation, field validation, and form validation.

• Examples of validation include checking for valid email addresses, ensuring tha...read more

AMV typically has 3 parameters: amplitude, mean, and variance.

• AMV stands for Amplitude, Mean, and Variance.

• It is commonly used in statistics to describe the distribution of a set of data.

• For example, in a normal distribution curve, the AMV parameters can help determine the shape and spread of the data.

Superdisintegrants are substances added to pharmaceutical formulations to promote rapid disintegration of tablets or capsules in the gastrointestinal tract.

• Crospovidone

• Croscarmellose sodium

• Sodium starch glycolate

• Cross-linked PVP

• Microcrystalline cellulose

Machines should be handled with care and following proper procedures to ensure safety and efficiency.

• Always follow operating instructions and safety guidelines provided by the manufacturer.

• Regularly inspect machines for any signs of wear or damage.

• Keep machines clean and well-maintained to prevent breakdowns.

• Use appropriate personal protective equipment when operating machines.

• Avoid distractions and stay focused while operating machinery.

• Properly shut down and secure machines...read more