10+ Quality Control Chemist Trainee Interview Questions and Answers

QC Person ensures products meet quality standards by conducting tests and inspections.

• Conducting tests and inspections on raw materials, in-process samples, and finished products

• Documenting and reporting test results

• Identifying and addressing quality issues

• Ensuring compliance with regulatory requirements

• Collaborating with other departments to improve product quality

• Maintaining and calibrating laboratory equipment

• Training and mentoring other employees

• Examples: QC chemist in ph...read more

UV detects conjugated systems, IR detects functional groups, NMR detects chemical environment

• UV detects conjugated systems such as double bonds and aromatic rings

• IR detects functional groups such as carbonyl and hydroxyl groups

• NMR detects the chemical environment of atoms in a molecule

• Examples include using UV to detect the presence of a double bond in a molecule, using IR to identify the functional groups in a compound, and using NMR to determine the structure of a molecule

Pharmaceutical companies are businesses that research, develop, manufacture, and market drugs and medical devices.

• Pharmaceutical companies are involved in the research and development of new drugs and medical devices

• They manufacture and market drugs and medical devices

• They are regulated by government agencies such as the FDA

• Examples of pharmaceutical companies include Pfizer, Johnson & Johnson, and Merck

GLP stands for Good Laboratory Practices. HACCP stands for Hazard Analysis and Critical Control Points. HACCP is used to ensure food safety.

• GLP stands for Good Laboratory Practices and includes guidelines for conducting experiments, analyzing data, and documenting results.

• HACCP stands for Hazard Analysis and Critical Control Points and is a systematic preventive approach to food safety.

• HACCP is used to identify and control potential hazards in food production processes to ens...read more

Spectroscopy is the study of the interaction between matter and electromagnetic radiation.

• It involves the use of various instruments to measure and analyze the absorption, emission, or scattering of light by a sample.

• It is used in various fields such as chemistry, physics, astronomy, and biology.

• Examples include UV-Vis spectroscopy, infrared spectroscopy, and nuclear magnetic resonance spectroscopy.

• It can be used to identify and quantify the components of a sample, determine ...read more

IR (Infrared Spectroscopy) analyzes molecular vibrations to identify compounds, typically in the range of 4000-400 cm⁻¹.

• IR stands for Infrared Spectroscopy, a technique used to identify molecular structures.

• The range of IR is typically from 4000 cm⁻¹ to 400 cm⁻¹.

• KBr (Potassium Bromide) is used in IR because it is transparent to IR radiation and does not absorb in the IR region.

• KBr pellets are commonly used for solid samples to create a uniform thickness for analysis.

• Other mat...read more

Titration is a quantitative analytical technique used to determine the concentration of a solute in a solution.

• Types of titration include: Acid-Base Titration (e.g., HCl vs NaOH)

• Redox Titration (e.g., KMnO4 vs Fe2+)

• Complexometric Titration (e.g., EDTA with metal ions)

• Precipitation Titration (e.g., AgNO3 with Cl- ions)

To prepare a normal solution, the number of equivalents of solute is dissolved in a specific volume of solvent. To prepare a molar solution, a specific number of moles of solute is dissolved in a specific volume of solvent.

• Determine the molar mass of the solute

• Calculate the number of moles of solute needed

• Measure the required volume of solvent

• Dissolve the calculated amount of solute in the solvent to make the solution

Gas Chromatography (GC) separates volatile compounds using a carrier gas and detects them with various detectors.

• Principle: GC separates components based on their volatility and interaction with the stationary phase.

• Carrier Gas: Commonly used gases include helium, nitrogen, and hydrogen.

• Detectors: Common detectors include Flame Ionization Detector (FID), Thermal Conductivity Detector (TCD), and Mass Spectrometer (MS).

• FID: Sensitive to hydrocarbons, widely used in petrochemica...read more

HPLC separates compounds based on polarity; GC separates based on volatility and vaporization.

• HPLC (High-Performance Liquid Chromatography) uses a liquid mobile phase to separate compounds.

• GC (Gas Chromatography) uses a gas mobile phase, typically for volatile compounds.

• In HPLC, separation occurs in a column packed with stationary phase; in GC, it occurs in a capillary column.

• HPLC is often used for pharmaceuticals, e.g., analyzing drug purity.

• GC is commonly used for analyzing...read more

Different types of titrations include acid-base, redox, complexometric, and precipitation titrations.

• Acid-base titrations involve the neutralization of an acid with a base or vice versa.

• Redox titrations involve the transfer of electrons between reactants.

• Complexometric titrations involve the formation of a complex between the analyte and titrant.

• Precipitation titrations involve the formation of a precipitate as the endpoint of the titration.