Senior Research Executive- Nutrition Science

A. Technology / Bioprocess development

• Develop new technologies / products using fermentation technology (Submerged Solid state), Microbiological processes, enzymatic processes , carry out fermenter process optimization and trouble shooting.
• Isolation and identification of microbial cultures, strain development (Mutation / gene modification), process optimization, fermenter parameter optimization using mathematical modeling.
• Perform protein purification using chromatography (HPLC, FPLC) and conduct enzyme assays for activity, specificity, and kinetics. Utilize mass spectrometry (MS) for protein identification and quantification, and apply spectroscopic methods (UV-Vis, fluorescence) for protein analysis.
• Prepare and maintain protein/enzyme stocks, develop protocols for extraction and purification.
• Perform electrophoretic techniques such as SDS-PAGE and Western blotting, with added advantage in handling bioinformatics tools.
• Experience in lab scale, pilot plant fermenter, centrifuges, filtration techniques (micro, ultra and nano filtration), different chromatography purification (Ion exchange and size exclusion), evaporation and spray drying
• Preparation of SOPs, STPs in compliance to the process. Active trouble shooting to minimize the various risks prior to execution and during execution.
• Experience with DOE and statistical analysis.
• Data generation, compilation, review, records and trends to formulate for the upstream/downstream process development order to support and make recommendations for improvements.
• Handful knowledge and independent experimental designing and execution of molecular biology related techniques viz., gene identification, cloning, over expression, etc.
• Experience with Laboratory Information Management Systems (LIMS) and SAP is a plus

B. People and Process Development

• Collaborate with members within and other verticals such as Business, production QA, QC and operation team.
• Work closely with colleagues from Fermentation division for process scale up

Accountability:

• Successful development, scale up and downstream processing of new products
• Successful delivery of technology to business
• Achievement of process improvements to improve cost efficiencies, product throughput etc.
• Ensure appropriate allocation of resources between the projects for its optimum utilization.

KPI :

• Number of technologies / products developed and lab and pilot scale
• Number of downstream processes developed for product purification
• No of Analytical method and assay development

Essential Attributes:

• Development of innovative new products / process using fermentation and enzyme technology to enable company to maintain its market leadership and increase its profitability.
• Ensure that infrastructure and facilities are conducive for creative work.
• Proactive planning for the better utilization and handling of resource / infrastructure
• Undertake troubleshooting on any issues / problems involving products, processes or technical procedures.
• Keep abreast of technical literature, domain knowledge and patents.
• Being proactive and seeing challenges as opportunities to take responsibility
• Flexibility to explore various new emerging new areas of the Nutrition Biosciences

Desired attributes:

• Bringing passion and excitement for hands-on experimental work, with strong creativity and curiosity to better understand fermentation and underlying systems.
• Excellent communication skills, data-keeping, and interpersonal skills
• Strong attention to detail, critical thinking and an aptitude for experimental planning.
• Good troubleshooting skills to deal with technical problems.
• Ability to work on multiple and simultaneous projects
• Good organizational and time management skills

Education Experience Requirements:

• M.Sc., in Biotechnology / Microbiology/Biochemistry / M.Tech in Biotechnology from a highly reputed institute.
• A minimum of 6-8 years of experience in handling of strain development, various Fermentation (such as bacterial, yeast and fungal), downstream processing techniques and product purification in prebiotics, probiotics and enzymes
• Proven track record of scientific excellence in developing new technologies and conducting scientific studies in Nutrition Biosciences