Q.1 if analyst mistankenly fit the column in opposite direction in HPLC what happen? Q.2 Define the type of impurities ? Q.3 what is force degradation. Q.4 What is the other methods used for reaction monitoring except HPLC. Q.4 Classifiaction of Solvent .

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Answering questions related to HPLC, impurities, force degradation, solvent classification, and reaction monitoring.

If a column is fitted in the opposite direction in HPLC, it can lead to inaccurate results.
Impurities can be classified as organic, inorganic, or residual solvents.
Force degradation is the process of intentionally subjecting a drug substance to stress conditions to evaluate its stability.
Other methods for reaction monitoring include UV-Vis spectroscopy, NMR spectroscopy, and mass spectrometry.
Solvents can be classified as polar protic, polar aprotic, or nonpolar.

Q.1 if analyst mistankenly fit the column in opposite direction in HPLC what happen? Q.2 Define the type of impurities ? Q.3 what is force degradation. Q.4 What is the other methods used for reaction monitoring except HPLC. Q.4 Classifiaction of Solvent .

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