Tell me about RRT AND Resolution

Question

Accepted Answer

RRT (Relative Retention Time) and Resolution are important concepts in chromatography.

RRT (Relative Retention Time) is the ratio of the retention time of a compound to the retention time of a reference compound.
RRT helps in identifying and comparing compounds in different chromatographic systems.
Resolution is a measure of how well two adjacent peaks are separated in a chromatogram.
Resolution is calculated by dividing the difference in retention times of two peaks by the sum of their peak widths.
Higher resolution indicates better separation of peaks.
For example, in gas chromatography, RRT can be used to compare the retention times of different compounds with a known reference compound.
Resolution is crucial in liquid chromatography to ensure accurate identification and quantification of compounds.

Accepted Answer

RRT is relative retention time and resolution is the gap between 2 peaks .

Popular interview questions of Quality Chemist