SAI Life Sciences
40+ Invicta eSolutions Interview Questions and Answers
Q1. What are the various Guage of ducting and which size we using which Guage
The gauge of ducting refers to its thickness and is determined based on the size and application of the duct.
The gauge of ducting ranges from 10 to 30, with lower numbers indicating thicker ducts.
The size of the duct determines the gauge to be used. Larger ducts generally require thicker gauges for structural integrity.
For example, a small residential HVAC system may use 24-gauge ducts, while a large commercial system may require 16-gauge ducts.
The gauge of ducting affects it...read more
Q2. What is the criteria for selecting reactor for particular reaction?
The criteria for selecting a reactor for a particular reaction depend on factors such as reaction kinetics, reactant properties, desired product, safety considerations, and economic feasibility.
Reaction kinetics: The reaction rate and mechanism influence the choice of reactor type.
Reactant properties: The physical and chemical properties of reactants, such as solubility, viscosity, and heat sensitivity, determine the reactor design.
Desired product: The desired product propert...read more
Q3. As per guide line's revit and nut and bolt sizes in angle frame
The question is asking about the guidelines for Revit and nut and bolt sizes in angle frame for HVAC engineering.
Revit is a software used for building information modeling (BIM) in HVAC engineering.
Guidelines for Revit include standards for modeling, annotation, and documentation.
Nut and bolt sizes in angle frame refer to the specific dimensions and types of fasteners used in constructing angle frames for HVAC systems.
These sizes may vary depending on the load requirements, m...read more
Q4. Which type of filters using in ahu and plenum
Different types of filters can be used in AHUs and plenums depending on the specific requirements.
Fiberglass filters are commonly used in residential and commercial buildings.
Pleated filters have a larger surface area and can capture smaller particles.
HEPA filters are highly efficient and can capture particles as small as 0.3 microns.
Activated carbon filters can remove odors and chemicals from the air.
Electrostatic filters use an electric charge to attract and capture particl...read more
Q5. Adding in n-buli nd dmf how to convertion
n-Buli and DMF can be used to convert certain functional groups through deprotonation and subsequent reactions.
n-Buli is a strong base commonly used for deprotonation reactions.
DMF (dimethylformamide) is a polar aprotic solvent that can facilitate reactions.
The combination of n-Buli and DMF can be used to convert certain functional groups such as alkyl halides to alkyl lithium compounds.
Care must be taken when handling n-Buli due to its pyrophoric nature.
Q6. Aldehyde to wittig reagent how to convertion
Aldehydes can be converted to Wittig reagents through a two-step process involving the formation of a phosphonium ylide.
React aldehyde with a phosphonium salt to form a phosphonium ylide
React the phosphonium ylide with an appropriate carbonyl compound to form the Wittig reagent
The Wittig reagent can then be used in a Wittig reaction to form an alkene product
Example: Conversion of benzaldehyde to benzylidene triphenylphosphorane
Q7. What is the in filtration and ex filtration
Infiltration and exfiltration are terms used in HVAC engineering to describe the movement of air into and out of a building.
Infiltration refers to the unintentional or uncontrolled flow of outdoor air into a building through cracks, gaps, or openings in the building envelope.
Exfiltration, on the other hand, is the opposite of infiltration and refers to the unintentional or uncontrolled flow of indoor air out of a building.
Both infiltration and exfiltration can have a signific...read more
Q8. What are the different type of pharmaceutical equipments you have come accross.
Pharmaceutical equipments include mixers, reactors, centrifuges, dryers, mills, and more.
Mixers: used for blending ingredients
Reactors: used for chemical reactions
Centrifuges: used for separating solids from liquids
Dryers: used for removing moisture from products
Mills: used for grinding and pulverizing materials
Tablet presses: used for compressing powders into tablets
Filtration systems: used for purifying liquids
Freeze dryers: used for drying products at low temperatures
Autoc...read more
Q9. Which equipments you are handling pervious
I have handled various equipments in my previous roles.
I have experience in handling heavy machinery such as cranes and forklifts.
I have also worked with specialized equipment such as MRI machines and X-ray machines in the medical field.
In my previous role, I managed a team responsible for maintaining and repairing manufacturing equipment such as conveyor belts and robotic arms.
I am familiar with various software and hardware tools used in the IT industry such as servers, rou...read more
Q10. What is the significance of boundary layer?
Boundary layer is a thin layer of fluid near a surface where the flow is affected by friction and viscosity.
Boundary layer plays a crucial role in determining the drag force on an object moving through a fluid.
It affects the heat transfer between the surface and the fluid.
It can also cause separation of the flow from the surface, leading to turbulence and reduced efficiency.
Examples include the boundary layer on an airplane wing or the surface of a ship moving through water.
Q11. What is the efficiency of h13 and h14
H13 and H14 are high-efficiency particulate air (HEPA) filters used in HVAC systems.
H13 filters can capture 99.95% of particles as small as 0.3 microns.
H14 filters can capture 99.995% of particles as small as 0.3 microns.
Both filters are commonly used in hospitals, cleanrooms, and other environments where air quality is critical.
The efficiency of these filters can vary depending on factors such as airflow rate and particle size distribution.
Q12. Can you describe NMR and how to interpret data
NMR is a technique used to analyze the structure and purity of molecules by measuring the magnetic properties of atomic nuclei.
NMR stands for Nuclear Magnetic Resonance and involves applying a magnetic field to a sample to measure the resonance frequencies of atomic nuclei.
Interpreting NMR data involves analyzing the chemical shifts, coupling constants, and peak integrations to determine the structure and purity of the molecule.
Different types of NMR experiments, such as 1H N...read more
Q13. What are the responsibilities in Quality Control department?
Q14. What are NMR values for solvents
NMR values for solvents are specific chemical shifts observed in nuclear magnetic resonance spectroscopy.
NMR values for solvents refer to the chemical shifts observed in nuclear magnetic resonance spectroscopy.
These values are used to identify and characterize solvents in chemical reactions.
Common solvents and their NMR values include chloroform (7.26 ppm), acetone (2.22 ppm), and methanol (3.34 ppm).
Q15. What are the core subjects in chemical engineering.
Core subjects in chemical engineering include thermodynamics, transport phenomena, reaction engineering, and process design.
Thermodynamics: study of energy and its transformations in chemical systems
Transport phenomena: study of momentum, heat, and mass transfer in chemical systems
Reaction engineering: study of chemical reactions and their kinetics
Process design: designing and optimizing chemical processes for production
Q16. What is NBS structure
NBS (N-bromosuccinimide) is a chemical compound used as a brominating agent in organic chemistry.
NBS is a white crystalline solid
It is commonly used in organic synthesis to selectively brominate allylic and benzylic positions
NBS is often used in conjunction with a radical initiator like AIBN to generate bromine radicals
Q17. What is pyridine structure
Pyridine is a heterocyclic aromatic compound with a six-membered ring containing five carbon atoms and one nitrogen atom.
Pyridine has a molecular formula of C5H5N
It is a colorless liquid with a strong odor similar to fish
Pyridine is commonly used as a solvent and precursor in organic synthesis
Q18. Write down the mass balance for an distillation column.
Mass balance for a distillation column involves accounting for the input and output streams of the column.
Mass balance equation: Input = Output + Accumulation
Input streams include feed, reflux, and steam
Output streams include distillate and bottoms
Accumulation can be calculated as the difference between input and output streams
The mass balance equation can be used to optimize the column's performance
Q19. What is unit operations and unit process?
Unit operations are individual steps in a process, while unit processes are a combination of unit operations to achieve a specific goal.
Unit operations are basic steps in a process that involve physical changes, such as mixing, filtration, and distillation.
Unit processes are a series of unit operations combined to achieve a specific chemical or physical transformation, such as a chemical reaction or purification.
Unit operations are often used in chemical engineering to descri...read more
Q20. What is cGMP and Q7 guidelines
cGMP and Q7 guidelines are quality control standards for pharmaceutical manufacturing.
cGMP stands for current Good Manufacturing Practices and is a set of regulations enforced by the FDA to ensure the quality, safety, and efficacy of pharmaceutical products.
Q7 guidelines are a part of the cGMP regulations and provide guidance on the manufacture of active pharmaceutical ingredients (APIs).
Both cGMP and Q7 guidelines emphasize the importance of documentation, quality control te...read more
Q21. N-alkylation of primary and secondary amines
N-alkylation is a process of adding an alkyl group to a primary or secondary amine.
N-alkylation can be achieved through various methods such as reductive amination, Gabriel synthesis, and Hoffmann degradation.
Primary amines can be selectively N-alkylated using alkyl halides and a base, while secondary amines require a more reactive alkylating agent such as an epoxide or an alkyl halide.
N-alkylation is an important reaction in organic synthesis and is used in the production of...read more
Q22. Reagents used for the functional groups interconversions
Reagents are used for interconversions of functional groups in organic synthesis.
Reagents are used to convert one functional group to another in organic synthesis.
Examples include Grignard reagents, reducing agents like LiAlH4, and oxidizing agents like KMnO4.
Reagents can also be used to protect functional groups during synthesis.
Common protecting groups include TBDMS for alcohols and Boc for amines.
Q23. Relationship between power watt and HP rating
1 horsepower is equal to 746 watts.
1 horsepower (HP) is a unit of power used in the imperial system
1 HP is equal to 746 watts (W) in the metric system
Watts are used to measure the rate of energy transfer or consumption
Horsepower is commonly used to rate the power of engines and motors
Q24. Which coloumns used in LCMS? What are C 18 and C4 coloumn?
C18 and C4 are commonly used reversed-phase columns in LCMS.
C18 and C4 refer to the type of stationary phase used in the column.
C18 has longer carbon chains and is more hydrophobic than C4.
C18 is commonly used for separating nonpolar compounds while C4 is used for separating polar compounds.
Other types of columns include C8, phenyl, and cyano columns.
The choice of column depends on the properties of the analyte and the separation goal.
Q25. Which types of cleaning in pharma industries
Cleaning in pharma industries includes equipment, facility, and personnel cleaning.
Equipment cleaning involves cleaning of manufacturing equipment, packaging equipment, and laboratory equipment.
Facility cleaning involves cleaning of floors, walls, ceilings, and HVAC systems.
Personnel cleaning involves cleaning of hands, gowns, and footwear.
Cleaning agents used in pharma industries are usually disinfectants and detergents.
Cleaning procedures must follow strict guidelines to en...read more
Q26. How many years of experience in api industry?
I have 8 years of experience in the API industry.
8 years of experience working with various APIs in different industries
Developed and implemented API strategies for multiple products
Experience in API design, development, and integration
Worked on API security and performance optimization
Collaborated with cross-functional teams to ensure API functionality and usability
Q27. What are couplings reactions
Coupling reactions are chemical reactions that involve the formation of a covalent bond between two molecules.
Coupling reactions involve the combination of two molecules to form a new compound.
These reactions often require a catalyst to facilitate the bond formation.
Coupling reactions can be used in organic synthesis to create complex molecules.
Examples of coupling reactions include the Suzuki coupling, Heck reaction, and Sonogashira coupling.
Q28. Some of the C- C bond formation reactions
C-C bond formation reactions involve the creation of a covalent bond between two carbon atoms.
Cross-coupling reactions, such as the Suzuki-Miyaura reaction, involve the coupling of two carbon-containing molecules using a metal catalyst.
Alkylation reactions involve the addition of an alkyl group to a carbon atom, forming a new C-C bond.
Aldol condensation reactions involve the formation of a new C-C bond between the alpha-carbon of one carbonyl compound and the carbonyl carbon ...read more
Q29. What is the principle of LCMS?
LCMS stands for Liquid Chromatography Mass Spectrometry. It is a technique used to separate, identify and quantify components in a mixture.
LCMS involves the use of a liquid chromatography column to separate the components of a mixture based on their chemical properties.
The separated components are then ionized and passed through a mass spectrometer to determine their mass-to-charge ratio.
LCMS is commonly used in drug discovery, environmental analysis, and forensic science.
LCM...read more
Q30. Protecting amine compund
Protecting amine compounds is important in organic synthesis to prevent unwanted reactions.
A common method for protecting amines is to convert them into their corresponding amine salts.
Another approach is to use protecting groups, such as Boc (tert-butyloxycarbonyl) or Fmoc (fluorenylmethyloxycarbonyl), which can be selectively removed later.
Protecting amines can also be achieved by converting them into amides or carbamates.
Care must be taken to choose a protecting group or m...read more
Q31. How to manage customer
Managing customers requires effective communication, understanding their needs, and building strong relationships.
Establish clear communication channels and set expectations
Listen actively to their needs and concerns
Provide regular updates and progress reports
Build trust and rapport through positive interactions
Address any issues or concerns promptly and professionally
Q32. How to do separation?
Separation can be achieved by identifying distinct components and implementing processes to isolate them.
Identify the components that need to be separated
Choose a suitable separation method such as filtration, distillation, or chromatography
Implement the chosen method to isolate the components
Ensure proper handling and disposal of separated components
Q33. All palladium catalysts reactions
Palladium catalysts are widely used in organic chemistry reactions.
Palladium-catalyzed cross-coupling reactions
Palladium-catalyzed C-H activation reactions
Palladium-catalyzed Heck reaction
Palladium-catalyzed Suzuki-Miyaura reaction
Palladium-catalyzed Sonogashira coupling
Palladium-catalyzed Buchwald-Hartwig amination
Q34. Tell me about Wet Analysis?
Q35. What is Deviation
Deviation refers to the difference between the actual and expected or planned outcome.
It is a measure of how far something is from the norm or standard.
It can be positive or negative depending on whether the actual outcome is better or worse than expected.
Examples include financial deviation, production deviation, and quality deviation.
Deviation can be calculated using statistical methods such as standard deviation or variance.
Q36. Tyapes of distillation
Distillation is a process of separating components of a mixture based on their boiling points. There are several types of distillation.
Simple distillation: used for separating components with large difference in boiling points
Fractional distillation: used for separating components with closer boiling points
Vacuum distillation: used for separating components with high boiling points
Steam distillation: used for separating components that are immiscible with water
Azeotropic dist...read more
Q37. Businesses handling in terms of revenue.
Businesses handle revenue through various channels such as sales, services, investments, and partnerships.
Revenue can be generated through sales of products or services.
Businesses can also earn revenue through investments in stocks, bonds, or real estate.
Partnerships with other companies can also contribute to revenue generation.
Diversifying revenue streams can help businesses mitigate risks and increase overall profitability.
Q38. All 1HNMR data
The question is asking for all the 1HNMR data.
1HNMR is a technique used in chemistry to determine the structure of molecules.
It provides information about the number and type of hydrogen atoms in a molecule.
The data obtained from 1HNMR can be used to identify functional groups and determine the purity of a sample.
Q39. What is about gmp
GMP stands for Good Manufacturing Practice, a set of guidelines ensuring products are consistently produced and controlled according to quality standards.
GMP is a system for ensuring that products are consistently produced and controlled according to quality standards.
It is designed to minimize the risks involved in any pharmaceutical production that cannot be eliminated through testing the final product.
Examples of GMP guidelines include proper sanitation, validation of equi...read more
Q40. What is organic science
Organic science is the study of living organisms and their interactions with the environment.
Focuses on the study of living organisms and their biological processes
Includes fields such as biology, ecology, and environmental science
Examines the relationships between organisms and their surroundings
Involves research on topics like genetics, evolution, and ecosystems
Q41. Unit operations and transport phenomena
Unit operations and transport phenomena are essential concepts in chemical engineering, involving processes like distillation, filtration, and heat transfer.
Unit operations refer to individual processes in chemical engineering, such as distillation, filtration, and crystallization.
Transport phenomena involve the movement of mass, energy, and momentum in chemical processes.
Examples of transport phenomena include heat transfer, mass transfer, and fluid flow.
Understanding unit o...read more
Q42. Telme ur self defence
I have basic self-defense skills to ensure my safety and the safety of others.
I have taken self-defense classes and learned techniques to protect myself in dangerous situations.
I am aware of my surroundings and can identify potential threats.
I know how to use common objects as improvised weapons if necessary.
I am trained in basic self-defense moves such as blocking, striking, and escaping holds.
I prioritize communication and de-escalation techniques to avoid physical confront...read more
Q43. Safety rules to follow
Safety rules to follow in a research scientist role
Always wear appropriate personal protective equipment (PPE) such as gloves, lab coats, and safety goggles
Follow proper procedures for handling chemicals and biological materials
Ensure proper ventilation in the laboratory
Regularly inspect and maintain laboratory equipment
Know emergency procedures and the location of safety equipment such as eyewash stations and fire extinguishers
Q44. What is science
Science is the systematic study of the natural world through observation and experimentation.
Science involves the use of evidence to understand the natural world.
It relies on observation, experimentation, and logical reasoning.
Scientific theories are constantly tested and revised based on new evidence.
Examples include biology, chemistry, physics, and astronomy.
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