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Leben Laboratories

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20+ Ace Lansdowne Investments Services Interview Questions and Answers

Updated 5 Feb 2024

Q1. If to make one tablet of paracetamol 500 mg API need then how many gram or kg API need to manufacture 10 lack tablet ?

Ans.

To manufacture 10 lakh tablets of paracetamol 500 mg API, you would need a certain amount of grams or kilograms of API.

  • To find the amount of API needed, we need to calculate the total quantity required for 10 lakh tablets.

  • First, convert 10 lakh tablets to the number of milligrams (mg) by multiplying by 500 mg (the dosage of each tablet).

  • Then, convert the total milligrams to grams or kilograms by dividing by 1000.

  • The resulting value will be the amount of API needed to manufact...read more

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Q2. What is the difference between qualitative and quantitative analysis?

Ans.

Qualitative analysis is subjective and deals with non-numerical data while quantitative analysis is objective and deals with numerical data.

  • Qualitative analysis deals with non-numerical data while quantitative analysis deals with numerical data.

  • Qualitative analysis is subjective while quantitative analysis is objective.

  • Qualitative analysis is used to gain insights and understanding while quantitative analysis is used to measure and quantify.

  • Examples of qualitative analysis in...read more

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Q3. What is the role of quality control department in pharmaceutical industry?

Ans.

The quality control department ensures that pharmaceutical products meet the required standards and regulations.

  • Ensuring compliance with regulatory requirements

  • Testing and analyzing raw materials, in-process samples, and finished products

  • Identifying and resolving quality issues

  • Maintaining documentation and records

  • Conducting audits and inspections

  • Collaborating with other departments to improve quality and efficiency

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Q4. How can you calculate dose of Any Drug for children ?

Ans.

Dose of any drug for children can be calculated based on their weight and age.

  • Calculate the child's weight in kilograms

  • Determine the appropriate dosage based on the child's age and weight

  • Consult drug reference guides or a pharmacist for specific dosing information

  • Adjust the dosage based on the child's response to the medication

  • Consider any potential side effects or drug interactions

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Q5. What is hard gelatin capsules and soft gelatin capsules ?

Ans.

Hard and soft gelatin capsules are two types of capsules used for oral medication.

  • Hard gelatin capsules are made of two pieces that fit together and are filled with dry or powdered medication.

  • Soft gelatin capsules are made of a single piece and are filled with liquid or semi-solid medication.

  • Hard capsules dissolve slowly in the stomach, while soft capsules dissolve quickly.

  • Soft capsules are often used for oil-based medications, while hard capsules are used for dry or powdered...read more

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Q6. Difference Between dissolution test and desentigration test?

Ans.

Dissolution test measures the rate of drug release from a dosage form while desentigration test measures the time taken for a dosage form to break down into smaller particles.

  • Dissolution test measures the amount of drug released from a dosage form over time

  • Desentigration test measures the time taken for a dosage form to break down into smaller particles

  • Both tests are important in ensuring the quality and efficacy of a drug

  • For example, a tablet that does not dissolve properly ...read more

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Q7. How many system in our body and explain ?

Ans.

There are 11 systems in the human body, each with a specific function.

  • The circulatory system pumps blood throughout the body.

  • The respiratory system helps us breathe.

  • The digestive system breaks down food and absorbs nutrients.

  • The nervous system controls and coordinates body functions.

  • The endocrine system produces hormones that regulate bodily functions.

  • The immune system defends against infections and diseases.

  • The lymphatic system helps remove waste and toxins from the body.

  • The...read more

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Q8. What you know about pharmaceutical industry?

Ans.

Pharmaceutical industry involves research, development, manufacturing, and distribution of drugs and medicines.

  • Pharmaceutical industry is highly regulated by government agencies such as FDA

  • It involves extensive research and development to create new drugs and improve existing ones

  • Manufacturing of drugs requires strict adherence to quality control standards

  • Distribution of drugs involves complex supply chain management

  • Examples of pharmaceutical companies include Pfizer, Johnson...read more

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Q9. What is blood and urine pH ?

Ans.

Blood pH is typically between 7.35 and 7.45, while urine pH can vary depending on diet and health.

  • Blood pH is tightly regulated by the body to maintain homeostasis

  • Urine pH can be affected by factors such as diet, medication, and certain medical conditions

  • Normal urine pH ranges from 4.6 to 8.0

  • Acidic urine (pH below 7.0) can indicate conditions such as metabolic acidosis or respiratory acidosis

  • Alkaline urine (pH above 7.0) can indicate conditions such as urinary tract infection...read more

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Q10. What is Hardness of tablet ?

Ans.

Hardness of tablet refers to the tablet's ability to withstand pressure without breaking or crumbling.

  • Hardness is an important parameter in tablet manufacturing.

  • It is measured using a hardness tester.

  • The hardness of a tablet affects its dissolution rate and bioavailability.

  • Different types of tablets have different hardness requirements.

  • For example, chewable tablets need to be softer than regular tablets.

  • The USP sets standards for tablet hardness.

  • Tablets that are too hard or t...read more

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Q11. What is room temperature ?

Ans.

Room temperature is the temperature range that is comfortable for humans and varies between 20-25°C (68-77°F).

  • Room temperature is the temperature range that is comfortable for humans.

  • It varies between 20-25°C (68-77°F).

  • It is the temperature at which most substances are stable and have a moderate rate of reaction.

  • It is important to maintain room temperature in certain industries like pharmaceuticals and food processing.

  • Room temperature can also vary depending on the location a...read more

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Q12. What is friability test ?

Ans.

Friability test is a method to determine the durability of tablets or granules by measuring the amount of powder generated due to friction.

  • It is a quality control test performed on tablets or granules.

  • The test involves tumbling the tablets or granules in a rotating drum for a specified time.

  • After the test, the tablets or granules are weighed to determine the amount of powder generated.

  • The test helps to ensure that the tablets or granules can withstand the rigors of handling a...read more

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Q13. Molecular weight of Hydrogen atom ?

Ans.

The molecular weight of a hydrogen atom is 1.008 u.

  • The molecular weight of an atom is the sum of the masses of its protons, neutrons, and electrons.

  • The molecular weight of hydrogen is calculated by adding the mass of its one proton and one electron.

  • The molecular weight of hydrogen is often used as a reference point for calculating the molecular weight of other elements and compounds.

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Q14. What is conductivity?

Ans.

Conductivity is the measure of a material's ability to conduct electricity.

  • Conductivity is a physical property of materials.

  • It is measured in siemens per meter (S/m) or millisiemens per centimeter (mS/cm).

  • Metals are good conductors of electricity, while non-metals are poor conductors.

  • Conductivity is affected by factors such as temperature, pressure, and impurities in the material.

  • It is used in various industries, including electronics, metallurgy, and water treatment.

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Q15. What is analytical balance?

Ans.

An analytical balance is a highly sensitive weighing device used to measure small quantities of substances.

  • It is used in laboratories for precise measurements

  • It can measure up to four decimal places

  • It is enclosed in a glass case to prevent air currents from affecting the measurement

  • It requires regular calibration to ensure accuracy

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Q16. Tell me types of coating?

Ans.

Coatings can be classified into various types based on their composition and application.

  • Organic coatings - made of carbon-based compounds

  • Inorganic coatings - made of non-carbon-based compounds

  • Metallic coatings - made of metals or metal alloys

  • Ceramic coatings - made of ceramics or glass

  • Polymer coatings - made of polymers or plastics

  • Electroplating coatings - deposition of a metal onto a conductive surface

  • Conversion coatings - chemical conversion of a metal surface to improve i...read more

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Q17. What is Tablet defect?

Ans.

Tablet defect refers to any deviation from the expected quality or standard of a tablet.

  • Tablet defects can include issues with the appearance, such as discoloration, chipping, or cracking.

  • Defects can also include issues with the tablet's weight, size, or shape.

  • Other defects may include issues with the tablet's dissolution rate or potency.

  • Common causes of tablet defects include problems with the manufacturing process, improper storage, or issues with the raw materials used.

  • Tab...read more

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Q18. Molecular weight of water ?

Ans.

Molecular weight of water is 18.01528 g/mol.

  • The molecular formula of water is H2O.

  • The atomic weight of hydrogen is 1.008 and oxygen is 15.999.

  • Multiplying the atomic weight of hydrogen by 2 and adding the atomic weight of oxygen gives the molecular weight of water.

  • The molecular weight of water is important in various chemical and biological processes.

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Q19. What is pH ?

Ans.

pH is a measure of the acidity or basicity of a solution.

  • pH stands for 'potential of hydrogen'

  • It is measured on a scale of 0-14

  • A pH of 7 is neutral, below 7 is acidic, and above 7 is basic

  • pH is important in many industries, including food and beverage production, agriculture, and medicine

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Q20. What is BMI ?

Ans.

BMI stands for Body Mass Index, a measure of body fat based on height and weight.

  • BMI is calculated by dividing a person's weight in kilograms by their height in meters squared.

  • It is used as a screening tool to identify potential weight problems in adults.

  • A BMI of 18.5 to 24.9 is considered healthy, while a BMI of 25 to 29.9 is overweight and a BMI of 30 or higher is obese.

  • However, BMI is not always an accurate measure of body fat and should be used in conjunction with other a...read more

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