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Eisai Pharmaceuticals

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10+ ALCHEMIST INFRASTRUCTURES Interview Questions and Answers

Updated 27 Mar 2025

Q1. How many hours maintenance engineer work at site?

Ans.

Maintenance engineers typically work 40 hours per week at the site.

  • Maintenance engineers usually work full-time hours, which is typically around 40 hours per week.

  • The specific number of hours may vary depending on the company and industry.

  • Some maintenance engineers may work overtime or on weekends to meet project deadlines or address emergencies.

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Q2. What would be the main focus of maintenance lead?

Ans.

The main focus of a maintenance lead is to oversee and coordinate maintenance activities to ensure equipment and facilities are in optimal condition.

  • Developing and implementing maintenance procedures and schedules

  • Supervising maintenance staff and contractors

  • Ensuring compliance with safety regulations

  • Managing maintenance budgets and inventory

  • Troubleshooting equipment issues and coordinating repairs

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Q3. What is ALCOA and ALCOA plus

Ans.

ALCOA is a set of principles used in data integrity to ensure data is Attributable, Legible, Contemporaneous, Original, and Accurate. ALCOA plus adds the principles of Complete, Consistent, Enduring, and Available.

  • ALCOA stands for Attributable, Legible, Contemporaneous, Original, and Accurate

  • ALCOA plus includes Complete, Consistent, Enduring, and Available

  • These principles are used in data integrity to ensure the quality and reliability of data

  • For example, data should be attri...read more

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Q4. How do give line clearance

Ans.

Line clearance is the process of ensuring that a production line is free from any previous materials or products before starting a new production run.

  • Inspect the production line to ensure it is clean and free of any leftover materials or products

  • Verify that all necessary equipment and tools are in place and functioning properly

  • Document the line clearance process to ensure traceability and compliance with regulations

  • Communicate with production team members to coordinate the li...read more

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Q5. What are IPQA roles

Ans.

IPQA roles refer to In-Process Quality Assurance responsibilities in manufacturing to ensure quality standards are met during production.

  • Monitoring and inspecting production processes to ensure compliance with quality standards

  • Identifying and addressing any deviations or non-conformances in real-time

  • Collaborating with production teams to implement corrective actions

  • Documenting and reporting quality issues and resolutions

  • Conducting audits and inspections of production areas

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Q6. How to work the Temperature Element and RTD?

Ans.

Temperature Element and RTD are used in control systems to measure temperature accurately.

  • Temperature Element is a device that measures temperature and converts it into a signal.

  • RTD (Resistance Temperature Detector) is a type of temperature sensor that operates on the principle that the electrical resistance of a metal changes predictably with temperature.

  • RTDs are commonly made of platinum, nickel, or copper.

  • RTDs provide accurate and stable temperature measurements.

  • Calibratio...read more

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Q7. What techniques are used in chromatography?

Ans.

Chromatography techniques separate mixtures based on component interactions with stationary and mobile phases.

  • 1. Thin Layer Chromatography (TLC) - Used for analyzing small samples, like pigments in plants.

  • 2. Gas Chromatography (GC) - Ideal for volatile compounds, such as in forensic analysis of substances.

  • 3. High-Performance Liquid Chromatography (HPLC) - Common in pharmaceuticals for purity testing.

  • 4. Ion Chromatography - Used for separating ions and polar molecules, often i...read more

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Q8. How to tackle unexpected problem in commercialization

Ans.

Addressing unexpected problems in commercialization requires adaptability, strategic planning, and stakeholder engagement.

  • Conduct a thorough risk assessment to identify potential issues early on.

  • Establish a cross-functional team to facilitate diverse perspectives and solutions.

  • Implement agile methodologies to quickly pivot strategies as needed.

  • Engage with stakeholders regularly to gather feedback and adjust plans accordingly.

  • Example: A pharmaceutical company faced regulatory ...read more

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Q9. How to work the Transmitter?

Ans.

Transmitters are devices used to send signals from a sensor to a control system. They typically convert physical parameters into electrical signals.

  • Transmitters convert physical parameters (such as pressure, temperature, flow rate) into electrical signals for transmission.

  • They are commonly used in industrial processes to monitor and control variables.

  • Transmitters can be wired or wireless, depending on the application.

  • Calibration and maintenance are important for accurate and ...read more

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Q10. What is chromatography?

Ans.

Chromatography is a technique for separating mixtures into their individual components based on their movement through a medium.

  • Used in laboratories for purifying chemicals.

  • Common types include gas chromatography and liquid chromatography.

  • In gas chromatography, volatile substances are separated based on their vaporization.

  • Liquid chromatography is often used in pharmaceuticals to analyze drug compounds.

  • Chromatography can also be used in food industry to test for contaminants.

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Q11. What is packing

Ans.

Packing is the process of arranging items into a container in a way that maximizes space and protects the items from damage during transportation.

  • Packing involves organizing items efficiently in a container or box

  • It is important to use appropriate packing materials such as bubble wrap, packing peanuts, or foam to protect fragile items

  • Proper packing can prevent items from shifting during transit and getting damaged

  • Examples of packing include packing clothes in a suitcase, pack...read more

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Q12. Any recent trouble shooting experience

Ans.

Recently, I resolved a complex data inconsistency issue in a machine learning model, enhancing its predictive accuracy.

  • Identified a data mismatch between training and validation datasets, leading to overfitting.

  • Implemented a systematic approach to clean and preprocess the data, ensuring consistency.

  • Utilized cross-validation techniques to verify model performance post-adjustments.

  • Collaborated with data engineers to automate data pipeline processes, reducing future discrepancie...read more

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