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Syngene International

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3.9

based on 1.9k Reviews

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39 Syngene International Jobs

Oligo Synthetic Chemist

Syngene

 · 

3.9

 based on 1.9k Reviews

2-5 years

Bangalore / Bengaluru

1 vacancy

Oligo Synthetic Chemist

Syngene International

posted 4hr ago

Job Role Insights

Flexible timing

Key skills for the job

Labour LCMS HRMS Organic Synthesis Synthetic Organic Chemistry Analytical Method Development

Job Description

  • The mandatory expectation for all roles as per Syngene safety guidelines
  • Overall adherence to safe practices and procedures of oneself and the teams aligned
  • Contributing to the development of procedures, practices, and systems that ensure safe operations and compliance to the companys integrity quality standards
  • Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times
  • Ensuring the safety of self, teams, and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace
  • Ensure all assigned mandatory training related to data integrity, health, and safety measures are completed on time by all members of the team including self compliance to Syngenes quality standards at all times
  • Hold self and their teams accountable for the achievement of safety goals
  • Govern and Review safety metrics from time to time
  • Core Purpose Of The Role
  • Personnel handling this profile will be responsible for performing reactions as per the requirement of the project
  • They are also responsible for documenting the observations in relevant notebooks
  • They are to follow instructions from the supervisor and work in a group (or individually) to accomplish the tasks in a timely and efficient manner
  • Role Accountabilities
  • Independently handling automated oligo synthesizer (KA-H16/Mermade-192/ KTA oligosynth)
  • Synthesis of DNA, RNA, ASOs, and modified oligonucleotides, conjugation using different reactions (amide, click, S-S, etc)
  • Method development for the purification (HPLC, IEX, SEC, PAGE) and characterization of the chemically modified and conjugated oligonucleotides by various analytical techniques (LCMS, MALDI, HRMS, etc) and data interpretation
  • Hands-on experience in handling purification instruments HPLC, AKTA-Pure, etc Excellent critical thinking, scientific skills, exposure to oligonucleotide discovery processes and current research trends
  • Team player, with experience in planning and conducting scientific experiments, focusing on deliverables of the project right from initiation to end
  • Ensure that the samples generated during synthesis are given for analysis and record subsequent results obtained and update the supervisor / group leader on the progress of synthesis and ensure samples are packed appropriately for shipment
  • Record the observations of experiment/reaction, results, utilization of resources and other activities related to the reaction in the laboratory or electronic lab notebook (ELN) following guidelines and in timely manner and ensure that the same is handled safely and confidentially
  • Ensure that the instrument / equipment is calibrated, undergone preventive maintenance, and are kept clean before use and in case of any breakdown, report to maintenance immediately
  • Ensure that they know the MSDS of the chemicals they are handling and aware of emergency response procedures in case of accidental spillage, leakage or fire and ensure proper waste segregation as per EHS norms
  • Always follow EHS and quality system requirements in the workplace ensuring individual safety and lab safety
  • Attend all mandatory trainings and update training records as and when trainings are completed
  • Always ensure confidentiality
  • Flexible to work in shift
  • Specific Requirements For This Role
  • Should be familiar with oligo-synthesis (nmol to mol to mmol scale) by using solid phase synthesis purification (RP-HPLC, IEX, PAGE, etc)
  • Familiar with operations of relevant apparatus instrument / equipment
  • Experience: 3-6years Skills And Capabilities
  • Should have deeper knowledge with concepts of oligo synthesis and reaction mechanisms
  • Candidate should be capable of solving synthetic problems independently
  • Should be excellent in purification and analytical interpretation skills
  • Familiar with operations of relevant apparatus instrument / equipment
  • Education
  • MSc (Chemistry / Biochemistry /Biotech) with 3-6 years of industrial Experience

    • Employment Type: Full Time, Permanent

    Read full job description

    Prepare for Synthetic Chemist roles with real interview advice

    What people at Syngene International are saying

    Synthetic Chemist salary at Syngene International

    reported by 4 employees with 13-17 years exp.
    ₹10.1 L/yr - ₹11.5 L/yr
    196% more than the average Synthetic Chemist Salary in India
    View more details

    What Syngene International employees are saying about work life

    based on 1.9k employees
    81%
    76%
    68%
    98%
    Flexible timing
    Monday to Friday
    No travel
    Day Shift
    View more insights

    Syngene International Benefits

    Submitted by Company
    Cafeteria
    Health Insurance
    Job Training
    Team Outings
    Submitted by Employees
    Cafeteria
    Health Insurance
    Job Training
    Team Outings
    Soft Skill Training
    Child care +6 more
    View more benefits

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    Syngene International Bangalore / Bengaluru Office Locations

    View all
    Bangalore / Bengaluru  (3)
    Bengaluru/Bangalore, Karnataka Office
    Headquarter
    Syngene International Ltd, Biocon Park, SEZ, Bommasandra Industrial Area – Phase-IV, Jigani Link Road, Bangalore 560099 Bengaluru/Bangalore, Karnataka
    560099
    Bengaluru/Bangalore, Karnataka Office
    Syngene International Ltd, Semicon Park, Tower 1, Electronic City – Phase-II Hosur Road, Bangalore 560100 Bengaluru/Bangalore, Karnataka
    560100

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