Scientist II, Molecular Biology

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cold Room/Freezers -22degreesF/-6degrees C, Loud Noises (Equipment/Machinery), Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Strong Odors (chemical, lubricants, biological products etc.), Will work with hazardous/toxic materials

About Team: Antibody team
The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity.

The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies.

The goal of the program is product development and creation of product specific information to promote research use.

Role & Responsibilities

To be a member in the molecular biology and sequencing core facility within an antibody development team through the advancement of innovative molecular biology techniques to enable high throughput recombinant antibody platforms.

Responsibilities:

• Perform in a fast- paced environment towards antibody development & testing
• Develop next generation methodologies, vector improvements, cloning strategies to facilitate high throughput workflows in recombinant antibody development platforms
• Informal leadership of team of scientists in matrix style operation, provide technical and operational supervision. Mentoring and training junior scientists in research, design and experimental execution, interpreting data and data presentation to collaborators and partners.
• Drive conceptualization within teams to enable development of successful protocols for effective transfer to operation teams.
• Provide inputs and guidance towards driving innovation and cross team collaborations.
• Partner with supporting functions such as product management, program management, operations, and business development to meet program goals.

Candidate Requirement:

Education & Experience levels:

• PhD with up to 3 years experience, or

• Masters degree with up to 8 years experience

Applicants should have a degree in a relevant life sciences field with a strong focus on next generation molecular biology, sequencing technologies and antibody development technologies.

Nature of experience:

• Experience with antibody development and engineering including hybridoma, display technologies, single B cell, and other antibody platforms
• Broad knowledge and experience in molecular biology, vector design, next generation cloning, miniaturizing strategies for high throughput gene to protein, Sanger and next generation sequencing technologies, antibody sequencing, protein and antibody design/engineering
• Excellent troubleshooting and problem-solving skills to identify and troubleshoot technical challenges and provide suitable solutions
• Experience in establishing new protocols and workflows is desirable
• Experience leading core facilities for molecular biology and/or sequencing will be a plus
• Authorship of peer-reviewed publications with post-doctoral experience and a strong, independent understanding of standard and emerging trends in the field are preferred.
• Flexibility and adaptability to work in a fast-paced research environment.
• Proficient in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism.

The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate.