RESEARCH ASSOCIATE/ Sr. RESEARCH ASSOCIATE

Educational qualifications

• M.Pharm (Pharmaceutics)

Key Responsibilities

• Read and understand client pre-formulation requirements
• Solid State and Solution State Characterization (interpretation of DSC, TGA and pXRD etc. data)
• Solubility assessment in Aqueous and Organic solvents simulated intestinal and gastric Medias.
• Bioavailability enhancement of compounds
• Excipient Compatibility Studies
• Preclinical formulation development of NCEs for pharmacokinetic, toxicology, & in vivo efficacy studies.
• Ability to work with wide variety of excipients, API and dosage forms
• Hands-on experience in strategy to come up with pharmaceutically acceptable salts for NCEs and their characterization and interpretation of the data to propose the suitable salt.
• Should know the know-how of various formulations combinations to address the solubility issues for various routes to perform PK studies in preclinical species.
• Should be able to develop dosage forms for therapeutic areas like oncology, metabolic disorders, inflammation etc.
• Should be able to develop HPLC-UV based methods for conducting formulation analysis under GLP and Non-GLP modes
• Good knowledge of chromatography DMPK (PRE-FORMULATIONS)
• Preparation of documents such as SOP’s for Laboratory instruments and reports for preformulation studies.

Experience required

• Good scientific knowledge about the role of pre-formulation in small molecule discovery.
• Basic knowledge of pharmacokinetics .
• Knowledge of various excipients and their permissible limits in preclinical and clinical setups.
• Handling of HPLC-UV/PDA
• Liquid chromatography.