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ProcDNA Interview Questions and Answers

Updated 9 Apr 2024

Q1. What are the stages in Granulation.

Ans.

The stages in Granulation include dry mixing, wet mixing, granulation, drying, sizing, and blending.

  • Dry mixing involves blending the active pharmaceutical ingredient with excipients.

  • Wet mixing involves adding a liquid binder to the dry powder mixture.

  • Granulation is the process of forming granules from the wet mass.

  • Drying removes moisture from the granules to improve stability.

  • Sizing involves breaking down oversized granules into smaller, uniform particles.

  • Blending combines th...read more

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Q2. How the pocket is formed in blister

Ans.

The pocket in a blister is formed by trapping air or gas between the product and the backing material.

  • Air or gas is trapped between the product and the backing material during the sealing process

  • The trapped air or gas creates a pocket within the blister pack

  • The pocket provides cushioning and protection for the product inside the blister pack

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Q3. What's LOD, how to perform.

Ans.

LOD stands for Level of Detail, it is a technique used in computer graphics to optimize the rendering of complex scenes.

  • LOD involves displaying objects with varying levels of detail based on their distance from the viewer.

  • It helps improve performance by reducing the number of polygons rendered for objects that are far away.

  • LOD can be implemented using techniques such as mesh simplification, texture resolution reduction, and level-of-detail models.

  • For example, in a video game,...read more

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Q4. What's is GMP,GDP,cGMP.

Ans.

GMP stands for Good Manufacturing Practices, GDP stands for Good Distribution Practices, and cGMP stands for current Good Manufacturing Practices.

  • GMP (Good Manufacturing Practices) are guidelines that ensure products are consistently produced and controlled according to quality standards.

  • GDP (Good Distribution Practices) are guidelines that ensure the quality and integrity of pharmaceutical products during distribution.

  • cGMP (current Good Manufacturing Practices) are updated a...read more

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Q5. Inprocess during Granulation.

Ans.

Inprocess during Granulation involves the mixing of powders with a liquid binder to form granules for further processing.

  • Granulation is a key step in the manufacturing of pharmaceutical tablets.

  • The process involves the wetting of powders with a binder solution to form granules.

  • The granules are then dried to remove moisture before being compressed into tablets.

  • Proper control of granulation parameters such as binder addition rate and mixing time is crucial for product quality.

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Q6. What is deviations what is CAPA

Ans.

Deviations are unexpected events or incidents that occur during the manufacturing process. CAPA is a corrective and preventive action taken to address deviations and prevent their recurrence.

  • Deviations are deviations from standard operating procedures or specifications.

  • CAPA is a process that involves identifying the root cause of the deviation, implementing corrective actions, and preventing recurrence.

  • Examples of deviations include equipment malfunction, human error, and env...read more

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