Principle behind to determine the end point in granulation .

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The principle behind determining the end point in granulation is to achieve the desired particle size and distribution for optimal product performance.

The end point in granulation is typically determined by monitoring the particle size distribution using techniques such as sieve analysis or laser diffraction.
The desired end point may vary depending on the specific product requirements, such as flowability, compressibility, and dissolution rate.
Factors influencing the end point include the type of granulation process used (wet, dry, or melt), the properties of the raw materials, and the equipment employed.
For example, in wet granulation, the end point may be reached when the granules have achieved a certain size and shape suitable for further processing into tablets or capsules.

Principle behind to determine the end point in granulation .

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