Macleods Pharmaceuticals
100+ ACS Recruitment Interview Questions and Answers
Q1. If you are HOD what will your action in particular case.
As the HOD, my action in a particular case would depend on the specific details and context of the case.
Assess the situation and gather all relevant information
Consult with team members and stakeholders
Analyze the available options and potential outcomes
Consider organizational policies and guidelines
Make a decision based on the best interests of the organization and its stakeholders
Implement the chosen course of action
Monitor and evaluate the results
Adjust the approach if nec...read more
Q2. What are various challenge test during primary packing?
Challenge tests during primary packing ensure the integrity of the packaging and its ability to protect the product.
Microbial challenge test
Leakage test
Drop test
Compression test
Accelerated aging test
Q3. Did you know about various sampling location in granulation?
Yes, I am aware of various sampling locations in granulation.
Sampling locations in granulation include in-process sampling, final product sampling, and stability sampling.
In-process sampling is done during the granulation process to ensure that the granules are of the desired size and consistency.
Final product sampling is done on the finished product to ensure that it meets the required specifications.
Stability sampling is done to test the shelf life of the product.
Sampling l...read more
Q4. What are various challenge test during secondary packing?
Challenge tests during secondary packing ensure product stability and integrity.
Seal integrity test
Drop test
Vibration test
Compression test
Temperature and humidity test
Q5. Air flow diagram between Cubical, AHU and DEH
Air flow diagram shows the path of air between cubical, AHU and DEH.
Air is drawn from the cubical into the AHU through the return air ducts.
The AHU conditions the air and sends it back to the cubical through the supply air ducts.
The DEH (Dedicated Exhaust Hood) removes contaminated air from the cubical and exhausts it outside.
The air flow diagram ensures proper ventilation and air quality in the cubical.
Q6. What is the pore size of filter paper used in filtration method
The pore size of filter paper used in filtration method varies depending on the type of filter paper.
The pore size can range from a few microns to several hundred microns.
Smaller pore sizes are used for fine filtration to remove smaller particles.
Larger pore sizes are used for faster filtration but may allow larger particles to pass through.
Common pore sizes for filter paper range from 0.2 to 10 microns.
Filter paper with a pore size of 0.45 microns is commonly used for microb...read more
Q7. What is unit process and unit operation
Unit process and unit operation are terms used in chemical engineering to describe different stages of a production process.
Unit process refers to a single chemical transformation that takes place during production, such as distillation or filtration.
Unit operation refers to a physical step in the production process, such as mixing or heating.
Unit processes and unit operations are often combined to create a complete production process.
Examples of unit processes include fermen...read more
Q8. What is mass transfer What is heat load How applying utilities to Glass lined Reactor How many types of Agitator What is fire extinguisher High vaccuum distillation
Questions related to chemical engineering and safety measures in a chemical plant.
Mass transfer refers to the movement of mass from one place to another in a chemical process.
Heat load is the amount of heat energy that needs to be removed from a system to maintain a desired temperature.
Utilities such as cooling water, steam, and nitrogen can be applied to a glass lined reactor to control the temperature and pressure of the reaction.
There are several types of agitators used in...read more
Q9. What is cpp and cqa? What is sampling protocol and how u select sampling quantity?
CPP and CQA are quality assurance terms used in pharmaceutical industry. Sampling protocol is a procedure to select representative samples.
CPP stands for Critical Process Parameters and CQA stands for Critical Quality Attributes.
CPPs are the variables that affect the quality of the product and CQAs are the characteristics that define the quality of the product.
Sampling protocol is a documented procedure that outlines the method of selecting representative samples from a batch...read more
Q10. Difference between HVAC and AC
HVAC refers to heating, ventilation, and air conditioning systems, while AC refers to air conditioning systems only.
HVAC systems include both heating and cooling components, while AC systems only provide cooling.
HVAC systems are used in larger buildings and homes, while AC systems are typically used in smaller spaces.
HVAC systems are more complex and require more maintenance than AC systems.
Examples of HVAC systems include central heating and cooling systems, while examples o...read more
Q11. What is the microbial limit of raw water for bacteria and fungi
The microbial limit of raw water for bacteria and fungi is typically set at 100 CFU/mL for bacteria and 50 CFU/mL for fungi.
Microbial limit for bacteria in raw water is usually set at 100 CFU/mL
Microbial limit for fungi in raw water is typically set at 50 CFU/mL
CFU stands for Colony Forming Units
Q12. Did you know about Hold Time Study?
Yes, Hold Time Study is a method used to determine the maximum time a product can be held before it deteriorates.
Hold Time Study is used in industries such as pharmaceuticals, food, and cosmetics.
It involves testing the product at various time intervals to determine its stability and shelf life.
The results of the study are used to establish expiration dates and storage conditions for the product.
Hold Time Study is an important aspect of quality assurance and regulatory compli...read more
Q13. At what load Maximum efficiency of transformer ?
The maximum efficiency of a transformer occurs at around 50-70% of its rated load.
The maximum efficiency of a transformer is typically achieved at a load that is around 50-70% of its rated capacity.
At lower loads, the transformer experiences less copper and iron losses, resulting in higher efficiency.
At higher loads, the transformer may experience increased losses due to heating and core saturation, leading to reduced efficiency.
Efficiency can vary depending on the design and...read more
Q14. Which cup borer is used for antibiotics assay as per BP
The cup borer used for antibiotics assay as per BP is the 8 mm cup borer.
The cup borer used for antibiotics assay as per BP is the 8 mm cup borer.
It is specified in the British Pharmacopoeia (BP) that the 8 mm cup borer should be used for antibiotics assay.
Using the correct cup borer size is crucial for accurate and consistent results in antibiotics assay.
Q15. What are the different methods of sterilization?
Sterilization methods include physical, chemical, and biological methods.
Physical methods include heat, radiation, and filtration.
Chemical methods include using gases like ethylene oxide or hydrogen peroxide.
Biological methods use living organisms like bacteria or enzymes.
Examples of sterilization methods include autoclaving, dry heat sterilization, and gas sterilization.
The choice of method depends on the type of material being sterilized and the level of sterilization requi...read more
Q16. What kind of inprocess do you conduct?
I conduct various in-process checks to ensure quality standards are met.
I check the production process at various stages to ensure it is running smoothly.
I verify that the correct materials are being used and that they meet quality standards.
I monitor the equipment to ensure it is functioning properly and calibrated correctly.
I perform visual inspections to ensure the product meets the required specifications.
I collect and analyze data to identify trends and potential issues....read more
Q17. Which buffer is used for antibiotics assay of erythromycin
Phosphate buffer pH 7.4 is used for antibiotics assay of erythromycin.
Phosphate buffer pH 7.4 is commonly used for antibiotics assay of erythromycin
The buffer helps maintain a stable pH for accurate assay results
Other buffers like acetate buffer or citrate buffer may also be used depending on the specific assay requirements
Q18. How bile tolerant gram negative bacteria tested quantitatively
Bile tolerant gram negative bacteria can be tested quantitatively using selective media containing bile salts.
Use MacConkey agar with bile salts to selectively grow and differentiate bile tolerant gram negative bacteria.
Count the number of colonies that grow on the agar to quantify the bacteria present.
Perform a series of dilutions and plate counts to determine the concentration of bile tolerant gram negative bacteria in a sample.
Q19. Details of old company etp and mee plant.? With calculations
The old company had an ETP and MEE plant. Details and calculations are provided.
The ETP (Effluent Treatment Plant) was designed to treat wastewater before it was discharged into the environment.
The MEE (Multiple Effect Evaporator) plant was used to concentrate the wastewater and recover valuable resources.
Calculations were performed to determine the efficiency of the ETP and MEE plant in treating and processing the wastewater.
For example, the ETP's efficiency could be calcula...read more
Q20. What is challange inprocess in primary and secondary?
The challenge in primary and secondary process is to ensure quality and consistency of the product.
Ensuring proper documentation and record keeping
Maintaining equipment and facilities
Training and monitoring personnel
Performing regular quality checks and audits
Addressing any deviations or non-conformances
Ensuring compliance with regulatory requirements
Maintaining product integrity throughout the supply chain
Q21. Method validation parameter and short brief for all
Method validation parameters ensure accuracy and reliability of analytical methods.
Method validation parameters include specificity, accuracy, precision, linearity, range, limit of detection, and limit of quantification.
Specificity ensures that the method measures only the analyte of interest.
Accuracy measures how close the measured value is to the true value.
Precision measures the reproducibility of the method.
Linearity measures how well the method can measure a range of con...read more
Q22. What do you expect a pharma...?
A pharmaceutical office boy is expected to assist in various administrative tasks and maintain cleanliness and organization in the office.
Assist in administrative tasks such as filing, photocopying, and data entry
Maintain cleanliness and organization in the office by cleaning and arranging furniture and equipment
Ensure proper stock of office supplies and restock as needed
Handle incoming and outgoing mail and deliveries
Run errands for the office, such as purchasing office supp...read more
Q23. How to creatieve a medicines a pharma....?
Creating medicines in pharma involves extensive research, testing, and regulatory approval.
Identify a medical need or condition to target
Conduct research to identify potential drug compounds
Test the compounds for safety and efficacy
Submit the drug for regulatory approval
Manufacture and distribute the drug
Continuously monitor and improve the drug's effectiveness and safety
Q24. What is the role of Medical Representative?
Medical Representatives are responsible for promoting and selling pharmaceutical products to healthcare professionals.
Building and maintaining relationships with healthcare professionals
Promoting pharmaceutical products to increase sales
Providing information and education on products to healthcare professionals
Attending conferences and meetings to stay updated on industry trends
Monitoring competitor activity and market trends
Meeting sales targets and objectives
Q25. How you can like in pharmaceutical companys.
I am interested in working in pharmaceutical companies because of my passion for the medical field and the opportunity to contribute to the development of life-saving drugs.
Passion for medical field
Opportunity to contribute to drug development
Interest in pharmaceutical industry
Desire to learn and grow in the field
Q26. Did you know about PQR?
Yes, PQR stands for Process Qualification Report.
PQR is a document that demonstrates the process validation of a manufacturing process.
It includes information on the process parameters, equipment used, and test results.
PQR is required by regulatory agencies to ensure the quality and consistency of the product.
It is an important part of the quality assurance process in industries such as pharmaceuticals and medical devices.
Q27. What is tailing factor
Tailing factor is a measure of peak asymmetry in chromatography, indicating the presence of tailing or fronting.
Tailing factor is calculated by dividing the distance from the peak apex to the leading edge of the peak by the distance from the peak apex to the trailing edge of the peak.
A tailing factor of 1 indicates a symmetrical peak, while values greater than 1 indicate tailing and values less than 1 indicate fronting.
Tailing factors are commonly used in chromatographic anal...read more
Q28. Detail explain validation sampling?
Validation sampling is a process of selecting a subset of data from a larger population to assess the accuracy and reliability of a validation method.
Validation sampling is used to evaluate the performance of a validation process or method.
It involves selecting a representative sample from a larger population.
The sample should be chosen randomly to ensure unbiased results.
The size of the sample should be sufficient to provide reliable conclusions.
Validation sampling can be us...read more
Q29. Which indicator uses in leak test?
The indicator used in leak test depends on the type of test being performed.
For pressure decay test, pressure gauges are used as indicators.
For bubble emission test, a solution of soap and water is used as an indicator.
For vacuum decay test, a vacuum gauge is used as an indicator.
Helium mass spectrometry is used as an indicator for helium leak test.
The choice of indicator depends on the sensitivity and accuracy required for the test.
Q30. What is the Process of drug administration.
The process of drug administration involves the delivery of medication into the body through various routes.
Different routes of drug administration include oral (by mouth), intravenous (into a vein), intramuscular (into a muscle), subcutaneous (under the skin), and topical (on the skin).
The route chosen depends on factors such as the type of medication, the desired onset of action, and the patient's condition.
After administration, the drug is absorbed into the bloodstream, di...read more
Q31. 1) What is chromatography? 2) What is spectroscopy? 3) What is molarity?
Chromatography is a technique used to separate and analyze mixtures. Spectroscopy is the study of the interaction between matter and electromagnetic radiation. Molarity is a measure of the concentration of a solution.
Chromatography involves passing a mixture through a stationary phase and a mobile phase to separate its components.
Spectroscopy can be used to identify the chemical composition of a substance by analyzing the way it interacts with different wavelengths of light.
M...read more
Q32. What challange show in NFD CAMERA?
NFD CAMERA faces challenges in detecting and identifying non-fluorescent dyes.
NFD CAMERA struggles to detect non-fluorescent dyes due to their lack of fluorescence.
This can lead to false negatives in identifying certain substances.
Alternative methods, such as colorimetric assays, may need to be used in conjunction with NFD CAMERA.
NFD CAMERA may also struggle with samples that have high levels of autofluorescence.
Regular calibration and maintenance of the equipment is necessar...read more
Q33. How many types of solution used in coating solution?
There are three main types of solutions used in coating: solvent-based, water-based, and powder coatings.
Solvent-based solutions use organic solvents to dissolve the coating material.
Water-based solutions use water as the main solvent for the coating material.
Powder coatings are applied as dry powder and then cured under heat to form a hard finish.
Q34. What is sensors explain it with examples temp, pressure, gas, flow sensor etc
Sensors are devices that detect and respond to input from the physical environment, such as temperature, pressure, gas, and flow.
Sensors are used to measure physical quantities and convert them into signals that can be read and interpreted by electronic devices.
Examples of sensors include temperature sensors, which measure the temperature of a system or environment, pressure sensors, which measure the pressure of a gas or liquid, gas sensors, which detect the presence of spec...read more
Q35. What is Casting and It's Processing
Casting is a manufacturing process in which a liquid material is poured into a mold and allowed to solidify.
The liquid material can be metal, plastic, or ceramic.
The mold is usually made of sand, plaster, or metal.
The solidified material is then removed from the mold and finished.
Casting is used to create complex shapes that would be difficult or impossible to make using other manufacturing processes.
Examples of cast products include engine blocks, jewelry, and dental crowns.
Q36. What is difference between unit operation or unit process
Unit operations involve physical changes in the material, while unit processes involve chemical changes.
Unit operations involve physical processes like filtration, distillation, and crystallization.
Unit processes involve chemical reactions like oxidation, reduction, and hydrolysis.
Unit operations are usually used in the initial stages of production, while unit processes are used in the later stages.
Unit operations focus on the physical aspects of production, while unit proces...read more
Q37. What is the work of agree cultural assistant?
Q38. Water flow diagram
A water flow diagram shows the path of water through a system or process.
Water enters the system through an inlet or source
It then passes through various stages of treatment or filtration
The treated water is stored in a tank or reservoir
Water is distributed to consumers through pipes or channels
Wastewater is collected and treated before being discharged
Q39. What is unit operation. Whats is heat transfer. Whats is relative volatility
Unit operation refers to a single step in a chemical engineering process. Heat transfer is the movement of thermal energy from one object to another. Relative volatility is a measure of the difference in vapor pressures between two components in a mixture.
Unit operation is a step in a chemical engineering process
Heat transfer is the movement of thermal energy
Conduction, convection, and radiation are the three types of heat transfer
Relative volatility is a measure of the diffe...read more
Q40. What was the difference between LCMS & GCMS?
LCMS is liquid chromatography mass spectrometry, while GCMS is gas chromatography mass spectrometry.
LCMS uses liquid as the mobile phase, while GCMS uses gas.
LCMS is more suitable for analyzing polar compounds, while GCMS is better for non-polar compounds.
LCMS typically has higher sensitivity and selectivity compared to GCMS.
LCMS is often used for analyzing small molecules, peptides, and proteins, while GCMS is commonly used for analyzing volatile organic compounds.
Q41. Tell me the acid stable protecting reagent?
Tert-butyldimethylsilyl (TBDMS) is an acid stable protecting reagent commonly used in organic synthesis.
TBDMS is commonly used to protect alcohols, amines, and carboxylic acids from acidic conditions during chemical reactions.
It is stable under acidic conditions, making it a popular choice for protecting groups in organic synthesis.
TBDMS can be removed using fluoride sources like tetrabutylammonium fluoride (TBAF) after the desired reaction is complete.
Q42. How to calibrate hplc
HPLC calibration involves preparing standard solutions, injecting them into the system, and adjusting parameters to ensure accurate and precise measurements.
Prepare standard solutions of known concentration
Inject the standard solutions into the HPLC system
Adjust parameters such as flow rate, column temperature, and detector wavelength to optimize separation and detection
Compare the retention times and peak areas of the standards to those of the sample to determine the concent...read more
Q43. What are the key Responsbility area of ABM
Key responsibility areas of ABM include sales management, team leadership, market analysis, and customer relationship management.
Sales management: Setting sales targets, monitoring performance, and implementing strategies to achieve sales goals.
Team leadership: Recruiting, training, and motivating sales team members to drive performance.
Market analysis: Conducting market research, identifying opportunities and threats, and developing plans to capitalize on market trends.
Custo...read more
Q44. The number of grams equivalent to solute that is dissolved in the one litre solution
The number of grams of solute dissolved in one liter of solution is known as the concentration of the solution.
Concentration is typically expressed in units such as grams per liter (g/L) or molarity (mol/L).
To calculate concentration, divide the mass of the solute by the volume of the solution.
For example, if 10 grams of salt are dissolved in 1 liter of water, the concentration of the solution is 10 g/L.
Q45. What Is Pharmacokinetic?
Pharmacokinetics is the study of how drugs are absorbed, distributed, metabolized, and excreted in the body.
Pharmacokinetics involves the processes of absorption, distribution, metabolism, and excretion of drugs in the body.
It helps in understanding how drugs move through the body, how they are broken down, and how long they stay in the system.
Factors such as age, weight, genetics, and liver function can affect pharmacokinetics.
Examples include studying how a drug is absorbed...read more
Q46. What is Prokinetics ?
Prokinetics are medications that enhance gastrointestinal motility and help improve the movement of food through the digestive system.
Prokinetics are commonly used to treat conditions like gastroesophageal reflux disease (GERD), gastroparesis, and functional dyspepsia.
They work by stimulating the muscles in the gastrointestinal tract to contract more frequently and efficiently.
Examples of prokinetic medications include metoclopramide, domperidone, and erythromycin.
These medic...read more
Q47. How good you are in maths and numbers
I am proficient in maths and numbers, with a strong background in quantitative analysis.
I have a degree in finance which required advanced math skills
I have experience analyzing financial data and creating forecasts
I am comfortable working with spreadsheets and financial models
Q48. Privious company process detail
The previous company had a well-defined production process with a focus on quality control.
The production process was divided into different stages with clear timelines and targets.
Quality control measures were implemented at every stage to ensure the final product met the required standards.
Regular audits were conducted to identify areas for improvement and implement corrective actions.
Efficient inventory management was maintained to avoid any delays or shortages in producti...read more
Q49. 1. How many types of pharmacopeia are there 2. Which parameters are checked during in process
There are three types of pharmacopeia: national, international, and industry-specific. Parameters checked during in process include purity, potency, and stability.
National pharmacopeia: set by individual countries to ensure quality and safety of drugs
International pharmacopeia: harmonized standards agreed upon by multiple countries
Industry-specific pharmacopeia: tailored to specific industries such as food or cosmetics
Parameters checked during in process: purity, potency, sta...read more
Q50. What is msds
MSDS stands for Material Safety Data Sheet.
MSDS provides information about the hazards and safety precautions related to a particular material or chemical.
It includes information about the composition, physical and chemical properties, health hazards, first aid measures, and disposal methods.
MSDS is required by law for all hazardous materials and chemicals used in the workplace.
It helps workers and emergency responders to handle hazardous materials safely.
Example: MSDS for a ...read more
Q51. Why we done fragility test?
Fragility test is done to determine the ability of a product to withstand mechanical shocks during transportation or handling.
To ensure the product's safety during transportation or handling
To identify potential weaknesses or defects in the product
To comply with regulatory requirements
To prevent damage or loss of the product
Examples include drop test, vibration test, and compression test
Q52. What is lod and loq
LOD and LOQ are the lowest detectable and quantifiable concentrations of an analyte, respectively.
LOD is the lowest concentration of an analyte that can be detected with a given method.
LOQ is the lowest concentration of an analyte that can be accurately quantified with a given method.
LOD and LOQ are important parameters in analytical chemistry and are used to determine the sensitivity of an analytical method.
For example, if the LOD of a method is 0.1 ng/mL, it means that the ...read more
Q53. What is pum cavitation
Pump cavitation is the formation and collapse of vapor bubbles in a pump due to low pressure.
Occurs when the pressure in a pump drops below the vapor pressure of the liquid being pumped
Can cause damage to the pump impeller and decrease pump efficiency
Can be prevented by ensuring proper suction pressure and avoiding high suction lift
Examples include noise and vibration in the pump, decreased flow rate, and damage to the impeller
Q54. What is the seals respans bility?
The seal's responsibility is to maintain balance in the ecosystem by controlling the population of certain species.
Seals are apex predators and play a crucial role in the food chain.
They help control the population of fish and other marine animals.
By doing so, they help maintain a healthy balance in the ecosystem.
Seals also serve as an indicator of the health of the ocean and its inhabitants.
Q55. What is tablet? What is the HPLC? What is the titration?
Tablet is a solid dosage form of medication. HPLC is a technique used for separating and analyzing compounds. Titration is a method used to determine the concentration of a substance in a solution.
Tablet is a pharmaceutical dosage form that contains a mixture of active substances and excipients compressed into a solid form.
HPLC (High Performance Liquid Chromatography) is a technique used in analytical chemistry to separate, identify, and quantify compounds in a mixture.
Titrat...read more
Q56. Disinfectant use and why
Disinfectant use is crucial for maintaining cleanliness and preventing the spread of harmful pathogens.
Disinfectants are used to kill or inactivate microorganisms on surfaces.
They are commonly used in healthcare settings, food preparation areas, and households.
Examples of disinfectants include bleach, alcohol-based solutions, and hydrogen peroxide.
Proper disinfectant use involves following manufacturer instructions for dilution and contact time.
Regular disinfection of high-to...read more
Q57. What's problems of particular machine?
The particular machine has a tendency to overheat frequently.
The machine's cooling system is not efficient enough.
The machine may have a clogged air filter.
The machine may be placed in an area with poor ventilation.
The machine may be overloaded with work.
The machine may have a faulty thermostat.
Regular maintenance and cleaning can prevent overheating issues.
Q58. Properties of cooling tower
Cooling towers are used to remove heat from a process or building by evaporating water.
Cooling towers are typically large, cylindrical structures that are used in industrial settings.
They work by using water to absorb heat from a process or building and then releasing it into the air through evaporation.
The two main types of cooling towers are natural draft and mechanical draft.
Natural draft cooling towers use the natural movement of air to cool the water, while mechanical dr...read more
Q59. What is ALCOA+ ?
ALCOA+ is a set of principles used in data integrity to ensure the reliability and accuracy of data.
ALCOA+ stands for Attributable, Legible, Contemporaneous, Original, Accurate, and Complete
It is commonly used in regulated industries such as pharmaceuticals and healthcare
Attributable means that all data should be traceable to its source
Legible means that data should be clear and easy to read
Contemporaneous means that data should be recorded at the time of the activity
Original...read more
Q60. What is Macrolide ?
Macrolides are a class of antibiotics that inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit.
Macrolides are commonly used to treat respiratory tract infections, skin infections, and sexually transmitted infections.
Examples of macrolides include azithromycin, clarithromycin, and erythromycin.
They are bacteriostatic, meaning they inhibit bacterial growth rather than killing the bacteria.
Q61. principle and working of valves , pumps , etc
Valves and pumps are mechanical devices used to control the flow of fluids in a system.
Valves are used to regulate the flow of fluids by opening, closing, or partially obstructing passageways.
Pumps are used to move fluids from one place to another by creating pressure or suction.
Valves can be classified based on their function (e.g. gate valve, ball valve) or based on their design (e.g. globe valve, butterfly valve).
Pumps can be classified based on their mechanism (e.g. centr...read more
Q62. suppliers supplying reactors , their names
Some of the suppliers supplying reactors include Company A, Company B, and Company C.
Company A
Company B
Company C
Q63. Which coating machine is there?
There are various types of coating machines used in different industries, such as vacuum coating machines, spray coating machines, and dip coating machines.
Vacuum coating machines are used for applying thin films to materials in a vacuum environment.
Spray coating machines use a spray gun to apply coatings onto surfaces.
Dip coating machines involve immersing the substrate into a tank of coating material to achieve uniform coverage.
Q64. Enlist Parameters of Compressed air validation?
Parameters of compressed air validation include purity, pressure, dew point, particle count, and microbial content.
Purity: Ensure absence of contaminants such as oil, water, and particles.
Pressure: Confirm air pressure meets specified requirements.
Dew Point: Measure moisture content to prevent corrosion and freezing.
Particle Count: Verify air cleanliness by counting particles of various sizes.
Microbial Content: Test for presence of bacteria and other microorganisms.
Examples: ...read more
Q65. How works our body described all system
The human body is a complex system consisting of various organs and organ systems that work together to maintain homeostasis.
The nervous system controls and coordinates all body functions.
The circulatory system transports oxygen and nutrients to cells and removes waste products.
The respiratory system brings in oxygen and expels carbon dioxide.
The digestive system breaks down food and absorbs nutrients.
The endocrine system produces hormones that regulate body functions.
The imm...read more
Q66. What is Tablets.
Tablets are portable computing devices that feature a touchscreen display and are primarily used for browsing the internet, watching videos, playing games, and running various applications.
Tablets are similar to smartphones but with larger screens.
They are lightweight and easy to carry around.
They typically have Wi-Fi or cellular connectivity for internet access.
Tablets often have built-in cameras for taking photos and videos.
They can be used for reading e-books and digital m...read more
Q67. What about HPLC method development
HPLC method development involves optimizing the conditions for separation and detection of analytes in a sample using high-performance liquid chromatography.
Selecting appropriate stationary and mobile phases
Optimizing flow rate and gradient conditions
Validating the method for accuracy and precision
Troubleshooting and optimizing as needed
Examples: developing a method for quantifying a drug in a biological sample, optimizing separation of complex mixtures for analysis
Q68. How to get Dosing activities
Dosing activities can be obtained through proper planning and execution of drug administration protocols.
Develop clear dosing guidelines based on patient characteristics and medication type
Ensure proper training and education of healthcare staff on dosing protocols
Implement regular monitoring and documentation of dosing activities
Utilize technology such as electronic prescribing and medication administration records
Collaborate with pharmacists and other healthcare professiona...read more
Q69. Types of heat exchanger
Heat exchangers are devices that transfer heat between two or more fluids.
Shell and tube heat exchanger
Plate heat exchanger
Double pipe heat exchanger
Spiral heat exchanger
Air cooled heat exchanger
Q70. What is capsule.
A capsule is a small, cylindrical container used for enclosing medicine or other substances.
Capsules are commonly used in the pharmaceutical industry to enclose medication in a solid dosage form.
They are made up of two gelatin or vegetarian-based shells that can be filled with powders, granules, or liquids.
Capsules can be either hard or soft, with hard capsules being used for dry ingredients and soft capsules for oils or liquids.
They are designed to be easily swallowed and di...read more
Q71. Current CTC and expected ctc?
Current CTC is confidential. Expectation is based on industry standards and my experience.
Current CTC is competitive within industry standards
Expectation is based on my experience and the responsibilities of the Senior Officer role
Open to negotiation based on benefits package and growth opportunities
Q72. What is fd
fd is not a commonly used abbreviation or acronym in any specific field.
There is no widely accepted definition for fd.
It could potentially stand for a variety of things depending on the context.
Without more information, it is impossible to provide a specific answer.
Q73. What is transformer??
A transformer is an electrical device that transfers electrical energy from one circuit to another through electromagnetic induction.
Transformers are used to increase or decrease the voltage of an alternating current (AC) power supply.
They consist of two coils of wire, called the primary and secondary coils, wrapped around a magnetic core.
When an AC voltage is applied to the primary coil, it creates a magnetic field that induces a voltage in the secondary coil.
Transformers ar...read more
Q74. 1. What is the oBR 2. What is the CIP
Short form acronyms, oBR stands for Optical Burst Receiver and CIP stands for Critical Infrastructure Protection.
oBR is a device used in optical communication networks to receive and process optical bursts of data.
CIP refers to the measures taken to protect critical infrastructure such as power grids, transportation systems, and communication networks from physical and cyber threats.
oBR is used in high-speed optical networks to improve data transmission efficiency.
CIP include...read more
Q75. csv for usfda guideline
CSV file for USFDA guidelines.
The CSV file should contain all the necessary information as per the USFDA guidelines.
The file should be properly formatted and easily readable.
Examples of information that may be included in the CSV file are drug names, dosages, adverse reactions, and clinical trial data.
Q76. Tell me Dispensing Procedure
Dispensing procedure involves verifying prescription, preparing medication, labeling, and delivering to patient.
Verify prescription details including patient name, medication name, dosage, and frequency.
Prepare medication as per prescription using appropriate equipment and techniques.
Label medication with patient name, medication name, dosage, and any special instructions.
Deliver medication to patient or designated location.
Maintain accurate records of dispensing activities.
E...read more
Q77. Attributes of RMG and FBD ?
RMG and FBD are both risk management techniques used in different industries.
RMG stands for Risk Management Group and is used in the financial industry to identify and manage risks associated with investments.
FBD stands for Failure Mode and Effects Analysis (FMEA) and is used in the manufacturing industry to identify potential failures in a product or process and their effects.
RMG focuses on financial risks such as market risk, credit risk, and operational risk.
FBD focuses on...read more
Q78. Types of fire
There are four types of fire: Class A, Class B, Class C, and Class D.
Class A fires involve ordinary combustibles like wood, paper, and cloth.
Class B fires involve flammable liquids like gasoline and oil.
Class C fires involve electrical equipment like appliances and wiring.
Class D fires involve flammable metals like magnesium and titanium.
Q79. Punch Description
Punch Description
A punch description is a detailed explanation of a manufacturing process.
It includes information about the materials used, the equipment used, and the steps involved.
For example, a punch description for a metal stamping process might include details about the type of metal being used, the thickness of the metal, the type of die being used, and the tonnage of the press.
A punch description is important for ensuring consistency and quality in the manufacturing p...read more
Q80. What's the improvement of product
The product has improved in terms of functionality, user experience, and performance.
Added new features to enhance functionality
Improved user interface for better user experience
Optimized performance for faster response times
Fixed bugs and issues reported by users
Increased product reliability and stability
Incorporated user feedback to improve overall product quality
Q81. Tell about 2nd Blind Study
A 2nd blind study is a research study where neither the participants nor the researchers know who is receiving the treatment or placebo.
Participants are randomly assigned to either the treatment group or the control group.
The purpose is to reduce bias and ensure the results are objective.
Examples include double-blind clinical trials in pharmaceutical research.
Q82. Candidate’s admin activity
Candidate has experience in administrative tasks such as scheduling, data entry, and report generation.
Candidate has experience scheduling appointments and meetings
Candidate is proficient in data entry and maintaining records
Candidate has generated reports using software like Excel or CRM systems
Q83. Sales target in the current company
Sales target in current company is $10 million for the year.
Sales target is set at $10 million for the current fiscal year.
The target is based on market analysis and growth projections.
Sales team is expected to meet or exceed the target to drive company revenue.
Regular performance reviews are conducted to track progress towards the target.
Q84. What is your Dispensing
Dispensing refers to the process of preparing and giving out medication to patients.
Dispensing involves accurately measuring and packaging medication according to a prescription.
It also involves labeling the medication with the patient's name, dosage, and instructions.
Dispensing requires knowledge of medication interactions and potential side effects.
Examples of dispensing tasks include counting pills, mixing liquids, and preparing injections.
Dispensing must be done in a ster...read more
Q85. What is quality control?
Quality control is a process used to ensure that products or services meet specific standards and requirements.
Quality control involves monitoring and testing products or services to identify defects or errors.
It aims to prevent defects from reaching customers and ensure consistent quality.
Examples include inspecting products on a production line, conducting audits of processes, and analyzing customer feedback.
Quality control may involve statistical analysis, process improvem...read more
Q86. What is Quality Assurance?
Quality Assurance is a process that ensures products or services meet specified requirements and standards.
Quality Assurance involves creating processes and procedures to prevent defects in products or services.
It focuses on continuous improvement and monitoring of processes to ensure consistent quality.
Examples include conducting audits, inspections, and testing to identify and address quality issues.
Quality Assurance is essential in industries such as manufacturing, healthc...read more
Q87. What is 21 CFR ?
21 CFR refers to the Code of Federal Regulations Title 21, which contains regulations related to food and drugs in the United States.
21 CFR is a set of regulations enforced by the US Food and Drug Administration (FDA)
It covers a wide range of topics related to food and drugs, including manufacturing, labeling, and safety
Compliance with 21 CFR is mandatory for companies that produce or sell food and drugs in the US
Examples of regulations in 21 CFR include requirements for good...read more
Q88. Types of validation
Validation is the process of checking if data is accurate and meets certain criteria.
Types of validation include data validation, form validation, and input validation.
Data validation ensures data is accurate and consistent, such as checking for valid email addresses.
Form validation checks if all required fields are filled out before submitting a form.
Input validation verifies that user input meets specified criteria, like checking for numerical values in a number field.
Q89. Types of equipments
Types of equipments include mechanical, electrical, electronic, and medical devices.
Mechanical equipments: tools, machinery, vehicles
Electrical equipments: switches, wires, transformers
Electronic equipments: computers, smartphones, TVs
Medical equipments: stethoscope, MRI machine, ultrasound device
Q90. What is mean by ALOCA?
ALOCA stands for As Last Observed Carried Forward. It is a statistical method used in clinical trials.
ALOCA is used to impute missing data in clinical trials.
It assumes that the missing data is the same as the last observed data.
ALOCA is considered a conservative approach to imputing missing data.
It is important to note that ALOCA should only be used when missing data is minimal and random.
ALOCA is not appropriate for imputing missing data in cases where the missing data is r...read more
Q91. What is NMR of xylene
NMR of xylene is a technique used to study the chemical structure and properties of xylene.
NMR stands for Nuclear Magnetic Resonance
It is a spectroscopic technique that uses the magnetic properties of atomic nuclei to determine the physical and chemical properties of molecules
NMR of xylene can provide information about the number and types of atoms in the molecule, as well as their arrangement and chemical environment
It can also be used to study the purity and concentration o...read more
Q92. Explain equipment qualification process?
Equipment qualification process ensures that equipment is suitable for its intended use by following a systematic approach.
Define equipment requirements and specifications
Select appropriate equipment based on requirements
Install and set up equipment according to manufacturer's guidelines
Perform operational and performance qualification tests
Document all qualification activities and results
Q93. What about dissolution
Dissolution refers to the process of dissolving a solid substance in a liquid to form a homogeneous solution.
It is an important parameter in drug development and quality control
It determines the rate and extent of drug absorption in the body
Factors affecting dissolution include particle size, solubility, pH, and temperature
Dissolution testing is performed using various apparatus such as USP apparatus 1, 2, 3, and 4
Examples of drugs with poor dissolution include carbamazepine ...read more
Q94. Method validation for Assay by HPLC
Method validation for Assay by HPLC involves testing the accuracy, precision, specificity, and linearity of the method.
The method should be tested for accuracy by comparing the results obtained with a reference standard or method.
Precision can be determined by analyzing multiple samples and calculating the standard deviation.
Specificity can be tested by analyzing samples with known interferences and ensuring they do not interfere with the assay.
Linearity can be determined by ...read more
Q95. What equipment you are handle
I handle a variety of production equipment including machinery, tools, and instruments.
Operate and maintain production machinery such as conveyor belts, mixers, and packaging machines
Use hand tools like wrenches, screwdrivers, and drills for assembly and repairs
Calibrate and monitor instruments like thermometers, pressure gauges, and pH meters
Ensure proper functioning of equipment to meet production targets and quality standards
Q96. Types of tablets
Tablets are solid dosage forms of medication that are compressed into a small, round, or oval shape for easy swallowing.
Tablets can be classified based on their release mechanism (immediate release, extended release, etc.)
They can also be categorized by their route of administration (oral, sublingual, buccal, etc.)
Examples include paracetamol tablets, ibuprofen tablets, and vitamin C tablets.
Q97. Types of capsule
Capsules are pharmaceutical dosage forms in which the drug is enclosed in a gelatin shell.
Capsules are made up of two main types: hard capsules and soft capsules.
Hard capsules are typically used for solid drugs and are made of two pieces that fit together.
Soft capsules are used for liquid or semi-solid drugs and have a single-piece gelatin shell.
There are also specialized capsules like enteric-coated capsules and sustained-release capsules.
Enteric-coated capsules have a speci...read more
Q98. What is acetaminophen
Acetaminophen is a common over-the-counter pain reliever and fever reducer.
Acetaminophen is also known as paracetamol.
It is commonly used to treat headaches, muscle aches, arthritis, backaches, toothaches, colds, and fevers.
It is often found in medications like Tylenol, Excedrin, and NyQuil.
Q99. What are variation guidelines
Variation guidelines are regulatory requirements for making changes to a product's marketing authorization.
Variation guidelines outline the procedures and documentation required for submitting changes to a product's marketing authorization.
Changes can include modifications to the manufacturing process, formulation, packaging, labeling, or indications for use.
Variation guidelines help ensure that changes do not compromise the safety, efficacy, or quality of the product.
Regulat...read more
Q100. Difference between DC's and plc
DC's are direct current power sources while PLCs are programmable logic controllers used for automation.
DC's provide constant voltage and current flow in one direction, used in simple circuits.
PLCs are digital computers used to control machinery and processes, programmed using ladder logic or other languages.
DC's are typically used for power supply in electronic devices, while PLCs are used for automation in industrial settings.
DC's are simpler and more basic compared to the ...read more
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