Lincoln Pharmaceuticals Production Officer Interview Questions and Answers

Bulk density is the mass of a powder per unit volume, while tapped density is the mass of a powder per unit volume after tapping. Compressibility index is a measure of the powder's ability to be compressed.

• Bulk density is determined by measuring the mass of a known volume of powder.

• Tapped density is determined by measuring the mass of a known volume of powder after tapping it a specified number of times.

• Compressibility index is calculated by subtracting the tapped density fro...read more

Deviation and Change control are processes used in pharmaceutical manufacturing to ensure quality and compliance with 21 CFR regulations.

• Deviation control is the process of documenting and investigating any deviation from established procedures or specifications.

• Change control is the process of managing changes to established procedures or specifications to ensure they are properly evaluated and approved before implementation.

• 21 CFR refers to the regulations set forth by the ...read more

Particle size distribution refers to the range of particle sizes in a sample.

• It is commonly measured using techniques such as sieving, sedimentation, and laser diffraction.

• Particle size distribution can affect the properties and behavior of a material, such as its flowability and reactivity.

• Examples of industries that may be concerned with particle size distribution include pharmaceuticals, food processing, and mining.

• Particle size distribution can also impact the performance...read more

The end point of RMG is granules and FBD is dried granules.

• RMG (Roller Compaction) is used to convert powder into granules.

• The end point of RMG is the formation of granules.

• FBD (Fluid Bed Dryer) is used to dry wet granules.

• The end point of FBD is the production of dried granules.

RMG, FBD, and sifter are equipment used in pharmaceutical manufacturing.

• RMG (Rapid Mixer Granulator) is used for wet granulation process.

• FBD (Fluid Bed Dryer) is used for drying and granulation of powders.

• Sifter is used for separating and grading of powders.

• All three equipment are commonly used in pharmaceutical manufacturing.

• RMG and FBD are often used together in a continuous manufacturing process.