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Jubilant Biosys

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10+ Jubilant Biosys Interview Questions and Answers

Updated 24 Feb 2025

Q1. How to handle and quench pyrophoric chemical in reaction.

Ans.

Pyrophoric chemicals can be handled and quenched by using inert gases, specialized containers, and proper disposal methods.

  • Use inert gases such as nitrogen or argon to displace air and prevent ignition.

  • Store and handle pyrophoric chemicals in specialized containers such as air-tight glass ampoules or sealed metal containers.

  • Dispose of pyrophoric chemicals properly by contacting a hazardous waste disposal company.

  • Examples of pyrophoric chemicals include alkali metals, metal hy...read more

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Q2. In vivo models and method related to therapeutic area

Ans.

In vivo models and methods are used to study the efficacy and safety of therapeutic interventions in living organisms.

  • In vivo models involve the use of animals such as mice, rats, and rabbits to study the effects of drugs and therapies.

  • Methods include administering the drug through various routes such as oral, intravenous, or subcutaneous injection.

  • In vivo studies can also involve imaging techniques such as MRI or PET scans to monitor the effects of the therapy on the body.

  • Ex...read more

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Q3. Name reactions based on palladium chemistry and copper chemistry

Ans.

Palladium and copper chemistry are widely used in organic synthesis. Some important reactions include Suzuki coupling, Heck reaction, Sonogashira coupling, and Ullmann reaction.

  • Suzuki coupling: cross-coupling reaction between an organoboron compound and an organic halide or triflate catalyzed by a palladium complex

  • Heck reaction: coupling of an aryl or vinyl halide with an alkene in the presence of a palladium catalyst

  • Sonogashira coupling: coupling of an aryl or vinyl halide w...read more

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Q4. Different oxidising and reducing agent for ester reduction,cyano reduction, alchol oxidation

Ans.

Different oxidising and reducing agents used for ester reduction, cyano reduction, and alcohol oxidation.

  • Ester reduction: Lithium aluminum hydride (LiAlH4), sodium borohydride (NaBH4), diisobutylaluminum hydride (DIBAL-H)

  • Cyano reduction: Lithium aluminum hydride (LiAlH4), sodium borohydride (NaBH4)

  • Alcohol oxidation: Chromium trioxide (CrO3), potassium permanganate (KMnO4), Jones reagent (CrO3/H2SO4)

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Q5. Tell me the name of any 5 oxidising reagents.??

Ans.

Some common oxidising reagents include potassium permanganate, hydrogen peroxide, chromic acid, ozone, and nitric acid.

  • Potassium permanganate

  • Hydrogen peroxide

  • Chromic acid

  • Ozone

  • Nitric acid

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Q6. Research work done in m.pharm

Ans.

Research work in M.Pharm involves studying and developing new drugs and therapies.

  • Researching the efficacy and safety of drugs

  • Developing new drug delivery systems

  • Studying the pharmacokinetics and pharmacodynamics of drugs

  • Investigating the mechanism of action of drugs

  • Conducting clinical trials to test new drugs

  • Analyzing drug interactions and side effects

  • Exploring natural products as potential sources of new drugs

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Q7. What is the pinacol pinacolone rearrangement

Ans.

Pinacol pinacolone rearrangement is a reaction in which a pinacol rearranges to form a ketone.

  • Involves the rearrangement of a 1,2-diol to a ketone

  • Requires an acidic catalyst such as sulfuric acid

  • Named after the starting material (pinacol) and the product (pinacolone)

  • Used in organic synthesis to form complex molecules

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Q8. Density difference, ethyl acetate/water/DCM

Ans.

The density difference between ethyl acetate, water, and DCM varies due to their different molecular weights and intermolecular forces.

  • Ethyl acetate has a lower density than water and DCM due to its lower molecular weight.

  • DCM has a higher density than water and ethyl acetate due to its higher molecular weight.

  • The intermolecular forces between the molecules also affect the density difference.

  • For example, hydrogen bonding between water molecules increases its density compared t...read more

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Q9. Any name reaction

Ans.

Grignard reaction

  • Named after French chemist Victor Grignard

  • Involves the reaction of an organomagnesium compound with a carbonyl compound

  • Forms a new carbon-carbon bond

  • Used in the synthesis of various organic compounds

  • Example: Grignard reaction between phenylmagnesium bromide and formaldehyde to form benzoic acid

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Q10. What is the process of Quality Management System (QMS)?

Ans.

QMS is a systematic approach to managing quality throughout an organization's processes.

  • Establishing quality objectives and policies

  • Implementing quality control measures

  • Conducting regular audits and reviews

  • Continuous improvement through corrective and preventive actions

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Q11. What are the steps involved in the audit process?

Ans.

The audit process involves planning, conducting fieldwork, reporting findings, and following up on corrective actions.

  • Planning phase includes defining objectives, scope, and criteria for the audit.

  • Conducting fieldwork involves gathering evidence, analyzing data, and evaluating processes.

  • Reporting findings includes documenting observations, conclusions, and recommendations.

  • Following up on corrective actions involves monitoring implementation of recommendations and verifying ef...read more

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Q12. What is chromatography? Principles, working of instrument

Ans.

Chromatography is a technique used to separate and analyze mixtures of chemicals based on their properties.

  • Chromatography involves a stationary phase and a mobile phase.

  • The sample is introduced into the mobile phase and travels through the stationary phase, separating the components based on their interactions with the stationary phase.

  • Different types of chromatography include gas chromatography, liquid chromatography, and ion exchange chromatography.

  • Chromatography is used in...read more

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Q13. What is the buffer solution?

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Q14. What is the beer lambert law

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