Hetero Biopharma Production Shift Incharge Interview Questions, Process, and Tips

Resin binding capacity refers to the maximum amount of resin that can be bound to a substrate.

• Resin binding capacity is influenced by factors such as surface area, porosity, and chemical composition of the substrate.

• It is important to optimize resin binding capacity to ensure efficient production processes.

• Examples of substrates with high resin binding capacity include activated carbon and ion exchange resins.

Column volume and bed height affect protein binding differently. Column selection for protein separation depends on various factors.

• Column volume refers to the total volume of the column, while bed height is the height of the resin bed inside the column.

• Protein binding is influenced by the surface area available for binding in the column, which is directly related to bed height.

• A larger column volume allows for more pr...read more

Neutralization is a chemical reaction between an acid and a base to form a neutral solution.

• Neutralization involves the combination of H+ ions from an acid and OH- ions from a base to form water and a salt.

• It is important in various industries such as pharmaceuticals, food and beverage, and wastewater treatment.

• Neutralization helps in controlling pH levels, preventing corrosion, and ensuring product quality.

• Example: Mi...read more

Good manufacturing practices are guidelines and procedures that ensure products are consistently produced and controlled according to quality standards.

• Ensure cleanliness and hygiene in the production area

• Follow standard operating procedures for all processes

• Regularly calibrate and maintain equipment

• Train staff on proper manufacturing practices

• Document all production activities for traceability