20+ Ziff Davis Interview Questions and Answers

Endotoxin is a type of toxin found in the cell wall of certain bacteria. USP chapters for water monitoring, media, and product are <1231>, <1116>, and <61>, respectively. The limits of cleanrooms are defined in USP chapter <797>. Four-hour monitoring in cleanrooms is done to ensure compliance with cleanliness standards.

• Endotoxin is a toxic substance present in the outer membrane of certain bacteria.

• USP chapter <1231> provides guidelines for water monitoring.

• USP chapter <1116>...read more

Calibration parameters of HPLC are used to ensure accurate and precise measurements of analytes.

• Calibration parameters include retention time, peak area, and peak height.

• Retention time is the time it takes for an analyte to pass through the column and be detected.

• Peak area and peak height are measures of the intensity of the analyte signal.

• Calibration curves are used to relate signal intensity to analyte concentration.

• Calibration parameters must be regularly checked and adjus...read more

Three mass and heat transfer operations at home and their correlation with manufacturing industry

• Boiling water for cooking (heat transfer) is similar to distillation in chemical industry

• Drying clothes (mass transfer) is similar to drying of solids in pharmaceutical industry

• Cooling drinks in refrigerator (heat transfer) is similar to cooling of chemicals in chemical industry

10N HCl has a pH of 1 and 10N NaOH has a pH of 14 due to their high concentration of hydrogen and hydroxide ions respectively.

• 10N HCl is a strong acid with a high concentration of hydrogen ions, resulting in a low pH of 1.

• 10N NaOH is a strong base with a high concentration of hydroxide ions, resulting in a high pH of 14.

• The pH scale ranges from 0 to 14, with 7 being neutral.

• The concentration of hydrogen ions determines acidity, while the concentration of hydroxide ions determ...read more

The calibration parameters of Balance monthly calibration include checking the accuracy and precision of the balance using standard weights.

• The balance is checked using standard weights of known mass.

• The accuracy and precision of the balance are evaluated.

• The calibration parameters may include the maximum allowable error and the number of calibration points.

• The calibration should be performed monthly to ensure accurate measurements.

• Documentation of the calibration should be k...read more

Deviations can be categorized based on their occurrence as frequent, occasional, or rare.

• Frequent deviations occur regularly and may require corrective action.

• Occasional deviations happen infrequently and may not require immediate action.

• Rare deviations are highly unusual and may require investigation to determine the cause.

• Examples of frequent deviations include equipment breakdowns or delays in production.

• Examples of occasional deviations include minor quality issues or del...read more

Materials can be charged using various methods such as direct contact, induction, or friction.

• Direct contact charging involves rubbing two materials together to transfer electrons.

• Induction charging involves bringing a charged object near the material to be charged, causing a transfer of electrons.

• Friction charging involves rubbing a material against a different material to transfer electrons.

• Materials can also be charged using static electricity or by exposure to a magnetic ...read more

CAPA effectiveness can be checked by reviewing data and verifying if the corrective actions have been implemented and resolved the issue.

• Review data to ensure the issue has not reoccurred

• Verify if the corrective actions have been implemented

• Check if the corrective actions have resolved the issue

• Conduct follow-up audits to ensure sustained effectiveness

• Document all findings and actions taken for future reference

OOS stands for Out of Specification and OOT stands for Out of Trend. They are used to describe deviations from expected results.

• OOS refers to a result that falls outside the predetermined specifications or acceptance criteria.

• OOT refers to a result that shows a trend deviating from the expected or historical data.

• Both OOS and OOT can indicate potential quality issues and require investigation and corrective actions.

• Examples of OOS and OOT include a product failing a potency t...read more

Solvents should be dispensed in a well-ventilated area, away from heat sources and open flames.

• Wear appropriate personal protective equipment (PPE) such as gloves and safety glasses.

• Use a designated dispensing area with proper ventilation.

• Avoid smoking or using open flames near the dispensing area.

• Use a funnel to prevent spills and minimize contact with skin.

• Dispose of solvents properly according to local regulations.

• Examples of solvents include acetone, ethanol, and methanol...read more

I'm sorry, I don't understand the question. Could you please rephrase it?

• The question seems unclear and may need to be rephrased

• It's possible that the interviewer made a mistake while asking the question

• Ask for clarification to ensure you understand what is being asked

Hold time varies for different stages of tablet production.

• Hold time refers to the duration for which a product is held at a particular stage before moving to the next stage.

• In tablet production, hold time varies for stages like granulation, compression, coating, and packaging.

• For example, the hold time for granulation can be around 24-48 hours, while for compression it can be around 2-3 hours.

• The hold time for coating can range from a few hours to a few days depending on the...read more

OOS handling procedure is the process of managing and investigating out-of-specification results.

• OOS results should be reported immediately to the appropriate personnel.

• Investigation should be conducted to determine the root cause of the OOS result.

• Corrective and preventive actions should be implemented to prevent recurrence.

• Documentation of the investigation and actions taken should be maintained.

• Examples of OOS results include failed product specifications, abnormal test re...read more

ISO 8 particle count standard values

• ISO 8 cleanrooms must maintain a maximum particle count of 3,520,000 particles per cubic meter of air sized 0.5 microns and larger

• ISO 8 cleanrooms must maintain a maximum particle count of 29,300 particles per cubic meter of air sized 5 microns and larger

• Regular monitoring and testing is required to ensure compliance with ISO 8 standards

Interlocks in a centrifuge are safety mechanisms that prevent the centrifuge from operating when certain conditions are not met.

• Interlock to prevent lid from opening while centrifuge is running

• Interlock to prevent centrifuge from operating if lid is not securely closed

• Interlock to prevent centrifuge from running if imbalance is detected

• Interlock to prevent centrifuge from running if temperature exceeds safe limits

Batch start up precautions are necessary to ensure safe and efficient operation.

• Perform a thorough inspection of equipment and systems before starting up

• Ensure all necessary safety equipment is in place and functioning properly

• Follow established procedures for starting up the batch process

• Monitor the process closely during start up to identify and address any issues

• Train all personnel involved in the start up process on proper procedures and safety protocols

SAP codes are used in maintenance breakdowns for tracking and categorizing issues.

• SAP codes help in identifying specific types of breakdowns or issues in maintenance processes

• They streamline the reporting and tracking of maintenance problems

• Using SAP codes can improve efficiency and accuracy in maintenance management

• For example, a code like 'PM01' could represent a preventive maintenance issue

Water system refers to the network of pipes, pumps, and other equipment used to supply water to a community or building.

• Water is typically sourced from a natural source such as a river or lake, or from a well.

• The water is then treated to remove impurities and ensure it is safe for consumption.

• The treated water is then transported through a network of pipes to homes and businesses.

• Water pressure is maintained through the use of pumps and valves.

• Wastewater is collected and trea...read more

The company vessel used varies depending on the company and its operations.

• Different companies use different vessels depending on their needs and operations.

• Some companies may use cargo ships for transporting goods, while others may use research vessels for scientific expeditions.

• Examples of company vessels include Maersk Line's Triple E class container ships and Ocean Infinity's Seabed Constructor.

• The type of vessel used may also depend on the industry, such as oil and gas c...read more

Isolators are used to prevent the flow of electricity between two points.

• Isolators are used to disconnect a circuit from its power source for maintenance or repair.

• They are also used to provide a physical barrier to prevent accidental contact with live parts.

• Isolators are commonly used in electrical distribution systems and industrial settings.

• Examples of isolators include circuit breakers, disconnect switches, and fuse holders.

The current company rules and regulations are outlined in the employee handbook.

• The employee handbook covers topics such as attendance, dress code, and workplace behavior.

• Employees are expected to follow all rules and regulations outlined in the handbook.

• Violations of company policies may result in disciplinary action, up to and including termination.

• The handbook is regularly updated to reflect changes in company policies and regulations.

Yes, I am willing to relocate for the right opportunity.

• I am open to relocating for career growth and new experiences

• I have relocated in the past for job opportunities

• I am flexible and adaptable to new environments

Biodata is a collection of personal information about an individual, typically used for recruitment and selection purposes.

• Biodata includes details such as name, age, education, work experience, skills, and hobbies.

• It is used by employers to assess a candidate's suitability for a job.

• Biodata can be collected through resumes, application forms, or online profiles.

• It helps in predicting job performance and organizational fit.

Recovery test procedure involves testing the system's ability to recover from failures and resume normal operation.

• Identify potential failure scenarios

• Simulate each failure scenario

• Observe how the system responds and recovers

• Document the results and any improvements needed

A transmitter is a device that sends out signals or information through airwaves or cables.

• Transmitters are commonly used in communication systems to send out radio signals, television signals, and wireless internet signals.

• They can also be used in remote controls, wireless microphones, and GPS devices.

• Transmitters convert electrical signals into electromagnetic waves for transmission.

• Examples of transmitters include radio transmitters, TV transmitters, and cell phone transmi...read more