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10+ Ciron Drugs & Pharmaceuticals Interview Questions and Answers

Updated 7 Feb 2025

Q1. Tell about Qualification activities for HVAC.

Ans.

Qualification activities for HVAC involve testing and verifying the performance of heating, ventilation, and air conditioning systems.

  • Conducting functional tests to ensure proper operation of HVAC systems

  • Performing air and water balancing to optimize system performance

  • Verifying compliance with industry standards and regulations

  • Documenting all testing and verification activities

  • Training personnel on proper operation and maintenance of HVAC systems

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Q2. Difference in biochem biotech nd micro

Ans.

Biochem is the study of chemical processes in living organisms, biotech is the use of living organisms to develop products, and micro is the study of microorganisms.

  • Biochem focuses on the chemical processes in living organisms

  • Biotech uses living organisms to develop products such as medicines and genetically modified crops

  • Microbiology is the study of microorganisms such as bacteria and viruses

  • All three fields are related to the study of living organisms but have different foc...read more

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Q3. Types of water use for pharma plants

Ans.

Water is used in pharmaceutical plants for various purposes such as manufacturing, cleaning, and cooling.

  • Water is used in the production of pharmaceutical drugs.

  • It is used for cleaning equipment and facilities.

  • Water is also used for cooling purposes in pharmaceutical plants.

  • Different types of water are used based on the specific requirements, such as purified water, water for injection, and clean steam.

  • Water is an essential component in the manufacturing process of pharmaceut...read more

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Q4. What is the definition of an SOP, and why is it considered so important in the current context of the pharmaceutical industry?

Ans.

SOP stands for Standard Operating Procedure. It is crucial in the pharmaceutical industry for ensuring consistency, quality, and compliance.

  • SOP is a set of step-by-step instructions compiled by an organization to help workers carry out routine operations.

  • In the pharmaceutical industry, SOPs are essential for maintaining quality control, ensuring compliance with regulations, and minimizing risks.

  • SOPs help in standardizing processes, reducing errors, and improving efficiency in...read more

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Q5. What is bacteria , fungi

Ans.

Bacteria and fungi are microorganisms that can be found in various environments and have different roles in nature and human life.

  • Bacteria are single-celled organisms that can be found in soil, water, air, and living organisms. Some bacteria are harmful and can cause diseases, while others are beneficial and play important roles in digestion, fermentation, and nitrogen fixation.

  • Fungi are a diverse group of organisms that include yeasts, molds, and mushrooms. They can be found...read more

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Q6. Calibration details of HPLC; GC; UV spectrophotometer; TLC;

Ans.

Calibration details of HPLC, GC, UV spectrophotometer, TLC

  • Calibration of HPLC involves checking the accuracy and precision of the instrument by using known standards.

  • GC calibration includes verifying the accuracy of the temperature, pressure, and flow rate settings.

  • UV spectrophotometer calibration involves checking the wavelength accuracy and linearity using standard solutions.

  • TLC calibration includes verifying the accuracy of the mobile phase composition and the distance tra...read more

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Q7. Procedure during analytical and how to handle against ICH guidelines.

Ans.

During analytical procedures, adherence to ICH guidelines is crucial. Proper handling is necessary to ensure accurate and reliable results.

  • Ensure that all equipment and instruments are calibrated and validated according to ICH guidelines.

  • Follow the appropriate analytical method as outlined in the ICH guidelines.

  • Document all steps taken during the analytical procedure, including any deviations from the ICH guidelines.

  • Perform appropriate data analysis and statistical evaluation...read more

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Q8. This environment soots you.

Ans.

Yes, this environment suits me well.

  • I thrive in fast-paced and dynamic environments

  • I enjoy working with a diverse group of individuals

  • I am comfortable with ambiguity and can adapt quickly to change

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Q9. What is Gram staining

Ans.

Gram staining is a technique used to differentiate bacteria into two groups based on their cell wall composition.

  • Gram staining involves applying a series of dyes to bacterial cells, which are then washed with alcohol and counterstained with a contrasting color.

  • Gram-positive bacteria retain the initial dye and appear purple under a microscope, while Gram-negative bacteria lose the dye and appear pink.

  • This technique is commonly used in microbiology to help identify and classify...read more

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Q10. Ready to work for minimum 3 to 5 years

Ans.

Yes, I am ready to commit to working for a minimum of 3 to 5 years.

  • I am committed to long-term growth and stability within the company.

  • I understand the importance of continuity and consistency in quality control processes.

  • I am excited about the opportunity to contribute to the company's success over an extended period of time.

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Q11. What is troubleshooting of HVAC Systems.

Ans.

Troubleshooting of HVAC systems involves identifying and resolving issues related to heating, ventilation, and air conditioning systems.

  • Identify the problem by observing and analyzing the system's performance.

  • Check for any visible signs of damage or malfunctioning components.

  • Inspect and test individual components such as motors, fans, filters, and thermostats.

  • Use diagnostic tools and equipment to measure temperature, pressure, and airflow.

  • Refer to system manuals and documenta...read more

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Q12. Definition of sterilization

Ans.

Sterilization is the process of killing or removing all forms of microbial life, including bacteria, viruses, fungi, and spores.

  • Sterilization can be achieved through physical methods such as heat, radiation, or filtration.

  • Chemical methods like using ethylene oxide gas or hydrogen peroxide can also be used for sterilization.

  • Common examples of sterilization include autoclaving, boiling, and using disinfectants.

  • Sterilization is crucial in medical settings to prevent the spread o...read more

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Q13. Types of sterilization

Ans.

Types of sterilization include heat, chemical, radiation, and filtration methods.

  • Heat sterilization: Autoclaving, incineration, dry heat

  • Chemical sterilization: Ethylene oxide, hydrogen peroxide

  • Radiation sterilization: Gamma radiation, electron beam

  • Filtration sterilization: Membrane filtration, depth filtration

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Q14. Calibration of dissolution

Ans.

Calibration of dissolution is a process to ensure accuracy and reliability of dissolution testing equipment.

  • Calibration involves verifying the accuracy of the equipment by comparing it to a known standard.

  • Regular calibration is essential to maintain the quality and consistency of dissolution testing results.

  • Calibration parameters may include temperature, rotation speed, and media pH.

  • Examples of calibration standards include USP and EP guidelines for dissolution testing.

  • Calibr...read more

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Q15. Calibration of Uv

Ans.

Calibration of UV involves verifying the accuracy of the UV equipment by comparing its readings to a known standard.

  • Calibration ensures that the UV equipment is providing accurate and reliable measurements.

  • Calibration involves adjusting the UV equipment if necessary to bring it into alignment with the standard.

  • Regular calibration is important to maintain the quality and accuracy of UV measurements.

  • Examples of calibration standards for UV equipment include certified reference ...read more

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