Apicore Pharmaceuticals Production Officer Interview Questions and Answers

The stages in Granulation include dry mixing, wet mixing, granulation, drying, sizing, and blending.

• Dry mixing involves blending the active pharmaceutical ingredient with excipients.

• Wet mixing involves adding a liquid binder to the dry powder mixture.

• Granulation is the process of forming granules from the wet mass.

• Drying removes moisture from the granules to improve stability.

• Sizing involves breaking down oversized gra...read more

Inprocess during Granulation involves the mixing of powders with a liquid binder to form granules for further processing.

• Granulation is a key step in the manufacturing of pharmaceutical tablets.

• The process involves the wetting of powders with a binder solution to form granules.

• The granules are then dried to remove moisture before being compressed into tablets.

• Proper control of granulation parameters such as binder addi...read more

LOD stands for Level of Detail, it is a technique used in computer graphics to optimize the rendering of complex scenes.

• LOD involves displaying objects with varying levels of detail based on their distance from the viewer.

• It helps improve performance by reducing the number of polygons rendered for objects that are far away.

• LOD can be implemented using techniques such as mesh simplification, texture resolution reduction...read more

The Knapp test kit is used to evaluate the visual inspection process through a machine.

• The Knapp test kit helps in assessing the accuracy and efficiency of visual inspection processes performed by machines.

• It can be used to identify any potential issues or defects in the inspection process.

• The kit typically includes various tools and materials to simulate different inspection scenarios.

• Results from the Knapp test kit c...read more

A clean room can be made by controlling air flow, using proper filtration systems, maintaining cleanliness, and implementing strict protocols.

• Control air flow to prevent contaminants from entering the room

• Use HEPA filters to remove particles from the air

• Regularly clean surfaces and equipment to prevent buildup of dust and debris

• Implement strict protocols for entering and exiting the clean room

Viable and non-viable monitoring involves assessing the presence of living and non-living organisms in a production environment.

• Viable monitoring involves counting living organisms such as bacteria or fungi using culture-based methods.

• Non-viable monitoring involves measuring total microbial counts, including both living and dead organisms, using methods like ATP bioluminescence.

• Regular monitoring helps ensure product q...read more

Cleaning validation is performed to ensure that the cleaning process effectively removes residues from equipment.

• Identify critical cleaning steps and equipment to be validated

• Establish acceptance criteria for residue limits

• Select appropriate analytical methods for detection

• Perform cleaning verification tests before validation

• Document all procedures and results for regulatory compliance

The number of tests available for tunnel and filling machine validation varies depending on the specific requirements of the production process.

• The number of tests for tunnel and filling machine validation can range from a few basic tests to a comprehensive validation protocol.

• Common tests include functionality testing, performance testing, and validation of critical process parameters.

• The number of tests may also depe...read more

The pocket in a blister is formed by trapping air or gas between the product and the backing material.

• Air or gas is trapped between the product and the backing material during the sealing process

• The trapped air or gas creates a pocket within the blister pack

• The pocket provides cushioning and protection for the product inside the blister pack

Expected CTC is negotiable based on company standards and job responsibilities.

• Expected CTC is dependent on various factors such as job role, experience, skills, and industry standards.

• The company may have a fixed salary range for the position, but it can be negotiable based on the candidate's qualifications.

• It is important to research the industry standards and the company's compensation policies before discussing the...read more

The stages in Granulation include dry mixing, wet mixing, granulation, drying, sizing, and blending.

• Dry mixing involves blending the active pharmaceutical ingredient with excipients.

• Wet mixing involves adding a liquid binder to the dry powder mixture.

• Granulation is the process of forming granules from the wet mass.

• Drying removes moisture from the granules to improve stability.

• Sizing involves breaking down oversized gra...read more

Inprocess during Granulation involves the mixing of powders with a liquid binder to form granules for further processing.

• Granulation is a key step in the manufacturing of pharmaceutical tablets.

• The process involves the wetting of powders with a binder solution to form granules.

• The granules are then dried to remove moisture before being compressed into tablets.

• Proper control of granulation parameters such as binder addi...read more

LOD stands for Level of Detail, it is a technique used in computer graphics to optimize the rendering of complex scenes.

• LOD involves displaying objects with varying levels of detail based on their distance from the viewer.

• It helps improve performance by reducing the number of polygons rendered for objects that are far away.

• LOD can be implemented using techniques such as mesh simplification, texture resolution reduction...read more