Director - PKS GH TA Lead

-Designs and conducts absorption, distribution, metabolism and excretion (ADME) research on compounds, drug agents and metabolites in pre-clinical and/ or clinical development.

Using a physicochemical approach, attempts to compile various data such as absorption and excretion rates and drug agent halflife in order to establish pharmacokinetic profiles of new chemical and/or molecular entities as well as determining the optimum and safe dosage forms for compounds that have been determined to have indications for various disease groups.

Responsible for developing protocols and/or preparing study documentation and findings to support domestic and inte national submissions of new drugs.

May include modeling and simulation.

May conduct studies using parametric optimization approach.

Manages research related to absorption, distribution, metabolism, and elimination of drugs in both animals and humans for a therapeutic area, product line or program.

Works closely with toxicology to document drug exposure in safety studies.

Conducts bioanalytical research on drug agents and metabolites in clinical studies, including management of studies conducted in outside labs.

Using pharmacokinetics, compiles data such as absorption and excretion rates in order to establish optimal and safe dosage rates.

Serves as liaison with marketing, conducting analytical and kinetic studies on new dosage regimens and/or new dosage forms.

-Implements and provides input to enable a division wide strategy for new discoveries and/or early development.

Enables impactful experimentation, project initiation, and decision making/progression by leading and empowering an interdisciplinary team of technical experts, broad scientific leaders, and lab associates or by creating and driving scientific, functional and technical communities surrounding own area of deep expertise and thought leadership.

Connects and inspires others around the Novartis mission.

• Leads a cross disciplinary team or brings together a broad functional community.
  
  
• May serve on leadership teams and/or decision boards to review projects and programs, assess progress, and provide multi directional input to progress the Division pipeline; shares and communicates key information to team.
  
  
• Drives continuous improvement and provides deep insight with collaborators within area of expertise, and/or works with own team to build scientific, technical or early development expertise and added value within department and across Division.
  
  
• Sets talent, leadership development, and culture priorities for own team or sets priorities for matrix team or functional community , in alignment with Novartis People Strategy and in close collaboration with leadership team colleagues.
  
  
• Co create top research organization to be one step ahead the market, contribute to long term talent and succession planning and/or collaborate to define talent attraction and development model surrounding own area of expertise.
  
  
• Sought after mentor and role model for talent development, coaching, and performance discussions across the organization.
  
  
• Responsible for initiating and driving critical programs and initiatives within own team and/or matrix community, and beyond department to advance, prioritize and renew the Division pipeline.
  
  
• Drives continuous improvement, strategic planning and culture building across the department.
  
  
• Accountable for success of project goals, cross divisional and/or external collaborations within direct and indirect team or highly collaborative, matrix working group.
  
  
• Reporting of technical complaints / adverse events / special case scenarios related to Novartis products within 24 hours of receipt -Distribution of marketing samples (where applicable)

• Discoveries -Developments -Experimental methods -Adherence to Novartis policy and guidelines -Project & stakeholder feedback

• Strategy Development.
  
  
• P&L or Unit Accountability.
  
  
• People Leadership.
  
  
• Collaborating across boundaries.
  
  

• Accountability.
  
  
• Biopharmaceutics.
  
  
• Chemistry.
  
  
• Clinical Pharmacology.
  
  
• Clinical Research.
  
  
• Clinical Trials.
  
  
• Critical Capabilities.
  
  
• Drug Development.
  
  
• Drug Discovery.
  
  
• Due Diligence.
  
  
• Electronic Components.
  
  
• Lifesciences.
  
  
• Mentorship.
  
  
• Non-Disclosure Agreements.
  
  
• Patient Care.
  
  
• Physics.
  
  
• Project Management.
  
  
• Quality Control.
  
  
• Scheduler.
  
  
• Stakeholders Management.
  
  
• Translational Medicine.
  
  
• Well-Being.
  
  

• English.
  
  

Accountability, Biopharmaceutics, Chemistry, Clinical Pharmacology, Clinical Research, Clinical Trials, Critical Capabilities, Drug Development, Drug Discovery, Due Diligence, Electronic Components, Lifesciences, Mentorship, Non-Disclosure Agreements, Patient Care, Physics, Quality Control, Scheduler, Stakeholders Management, Translational Medicine, Waterfall Model, Well-Being