Asso Scientist IVIVC (Biopharmaceutics)

Sandoz is going through an exciting and transformative period as a global leader and pioneering provider of sustainable Biosimilar and Generic medicines.

Now as an independently listed company, Sandoz aims to increase its strategic focus, operate with greater agility, set clearer business objectives, enhance shareholder returns, and strengthen its culture for us, the Sandoz associates. This is an exciting time in our history, and by creating a new and ambitious path, it will provide a unique opportunity for us all, both professionally and personally. Join us as a Founder of our new Sandoz!

-Plan and perform scientific experiments (or pilot plant processes) for the preparation and timely delivery of drug substances (DS), drug products (DP), processes and procedures in collaboration within a multifunctional project team coordinated by a Project leader. Contribute to maintenance of lab instruments/infrastructure. -SANDOZ: Plan and perform scientific experiments (or pilot plant processes) for the development and timely delivery of drug products (DP), processes and procedures in collaboration within a multifunctional project team coordinated by a Project leader. Contribute to maintenance of lab instruments/infrastructure. -Support development projects aiming the development of stable, bioequivalent, robust and cost competitive dosage forms -Design and manage experiments/batches for simple/low complexity products under supervision, provide related scientific documentation -Plan and execute experiments in agreement with quality risk management and GDevP /GMP -Assists in the preparation of and reviews of the technological part of dossier

• Develop and optimize new dissolution method (Biorelevant and discriminatory dissolution method) mimicking the physiological system
• Independently perform and document solubility experiments, dissolution method activities and other characterization methods (DT, solubility, IDR, Viscosity etc).
• Testing of various developmental formulations in biorelevant and discriminatory dissolution methods
• Analysis of samples using various analytical techniques like HPLC/UPLC and spectrophotometric methods. Addressing the trouble shoots in chromatographic methods
• Write protocols, reports or lab procedures based on templates under expert s supervision.
• Document Risk assessment at pre-evaluation stage under expert s guidance.
• Knowledge of PBPK/IVIVC models.
• Assist modeling expert in developing various in-silico tools like Gastroplus/Phoenix WinNonlin etc.
• Work in close collaboration with multifunctional project team

Essential Requirements:

• Experience of 2-4 years in Analytical development from generic pharmaceutical industry.
• M Pharm (Pharmaceutical Analysis, Pharmaceutics); M Sc (Analytical Chemistry); B Pharm
• Attributes required of the job e.g. the ability to work independently; the ability to work in a team; shows initiative; able to work with all levels of staff.
• Strong written and oral communication skills.

Environment, Health And Safety (Ehs), Laboratory Equipment, Manufacturing Process, Materials Science, Process Simulation, Sop (Standard Operating Procedure)