variant call on observed by reference sample

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Variant calling is a process of identifying differences between a sample and a reference genome.

Variant calling is used in genomics to identify genetic variations that may be associated with disease or other traits.
It involves comparing a sample genome to a reference genome to identify differences, or variants, such as single nucleotide polymorphisms (SNPs) or insertions/deletions (indels).
Variant calling can be done using various software tools, such as GATK, FreeBayes, and SAMtools.
The accuracy of variant calling depends on the quality of the reference genome and the sequencing data.
Variant calling is an important step in many applications, including cancer genomics, population genetics, and personalized medicine.

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