Shilpa Medicare Interview Questions, Process, and Tips

To convert reverse phase to normal phase in HPLC, change the stationary phase from non-polar to polar.

• Replace the non-polar stationary phase with a polar one

• Use a polar mobile phase

• Adjust the pH of the mobile phase to match the pKa of the analyte

• Optimize the gradient elution conditions

• Verify the separation using appropriate standards

The flow of water, methanol, and isopropanol can be determined by measuring their respective viscosities and densities.

• Viscosity and density of each liquid must be measured

• The flow rate can be calculated using the Hagen-Poiseuille equation

• The flow rate will vary depending on the pipe diameter and pressure

• The flow rate can be optimized by adjusting the pipe diameter and pressure

• The flow rate of each liquid can be compar

There is no magic solution.

• There is no one-size-fits-all solution for quality control.

• Quality control requires a combination of various techniques and processes.

• Continuous improvement and adaptation are key in quality control.

• Examples of quality control techniques include statistical process control, Six Sigma, and Lean manufacturing.

If the weight of the Blend is less than the Given Limit during Compression Line Clearance, the IPQA should take appropriate action.

• The IPQA should immediately stop the compression process.

• They should inform the production team and supervisor about the issue.

• Investigate the cause of the weight discrepancy, such as equipment malfunction or incorrect formulation.

• Document the incident and any observations made during the p...read more